| http://purl.uniprot.org/citations/7592997 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7592997 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7592997 | http://www.w3.org/2000/01/rdf-schema#comment | "A novel protein-tyrosine phosphatase, PTP phi, was cloned from a murine macrophage cDNA library. As a result of alternative splicing, macrophage PTP phi mRNAs are predicted to encode two membrane-spanning molecules and a cytosolic enzyme with identical catalytic domains. The membrane-spanning forms differ in the juxtamembrane region, while a start codon downstream of this region is utilized in the translation of the putative cytosolic form. Expression of PTP phi mRNA is low and restricted to macrophage cell lines, macrophage-rich tissues, and brain, kidney, and heart. The mRNA in macrophages and heart is approximately 2.8 kilobases (kb). However, a approximately 5.5-kb transcript in brain and kidney indicates a fourth isoform encoding a large extracellular domain. The approximately 5.5-kb PTP phi brain mRNA encodes the mouse homolog of GLEPP1, a recently reported glomerular epithelial protein. The level of expression of the mRNA encoding the cytosolic form was very low, and only the membrane-spanning proteins (43 and 47 kDa) could be detected in macrophages. Following addition of colony stimulating factor-1 to quiescent BAC1.2F5 macrophages, PTP phi mRNA and protein were down-regulated. The restricted expression of the shorter isoforms of PTP phi and their regulation by colony stimulating factor-1 in macrophages suggest that PTP phi may play a role in mononuclear phagocyte survival, proliferation, and/or differentiation."xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.270.45.27339"xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.270.45.27339"xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/author | "Dominguez M.G."xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/author | "Dominguez M.G."xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/author | "Pixley F.J."xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/author | "Pixley F.J."xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/author | "Lee P.S."xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/author | "Lee P.S."xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/author | "Stanley E.R."xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/author | "Stanley E.R."xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/author | "Einstein D.B."xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/author | "Einstein D.B."xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/pages | "27339-27347"xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/pages | "27339-27347"xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/title | "A heteromorphic protein-tyrosine phosphatase, PTP phi, is regulated by CSF-1 in macrophages."xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/title | "A heteromorphic protein-tyrosine phosphatase, PTP phi, is regulated by CSF-1 in macrophages."xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/volume | "270"xsd:string |
| http://purl.uniprot.org/citations/7592997 | http://purl.uniprot.org/core/volume | "270"xsd:string |