| http://purl.uniprot.org/citations/7596406 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7596406 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7596406 | http://www.w3.org/2000/01/rdf-schema#comment | "Some cases of Alzheimer's disease are inherited as an autosomal dominant trait. Genetic linkage studies have mapped a locus (AD3) associated with susceptibility to a very aggressive form of Alzheimer's disease to chromosome 14q24.3. We have defined a minimal cosegregating region containing the AD3 gene, and isolated at least 19 different transcripts encoded within this region. One of these transcripts (S182) corresponds to a novel gene whose product is predicted to contain multiple transmembrane domains and resembles an integral membrane protein. Five different missense mutations have been found that cosegregate with early-onset familial Alzheimer's disease. Because these changes occurred in conserved domains of this gene, and are not present in normal controls, they are likely to be causative of AD3."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.org/dc/terms/identifier | "doi:10.1038/375754a0"xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.org/dc/terms/identifier | "doi:10.1038/375754a0"xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "Ikeda M."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "Ikeda M."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "Liang Y."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "Liang Y."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "Li G."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "Li G."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "Lin C."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "Lin C."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "Chi H."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "Chi H."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "Rommens J.M."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "Rommens J.M."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "Bruni A.C."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "Bruni A.C."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "Fraser P.E."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "Fraser P.E."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "Roses A.D."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "Roses A.D."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "St George-Hyslop P.H."xsd:string |
| http://purl.uniprot.org/citations/7596406 | http://purl.uniprot.org/core/author | "St George-Hyslop P.H."xsd:string |