| http://purl.uniprot.org/citations/7599316 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7599316 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7599316 | http://www.w3.org/2000/01/rdf-schema#comment | "We characterized a nuclear gene and its corresponding cDNA encoding beta-tubulin (gene TubB1) of the marine red alga Chondrus crispus. The deduced TubB1 protein is the most divergent beta-tubulin so far reported with only 64 to 69% amino acid identity relative to other beta-tubulins from higher and lower eukaryotes. Our analysis reveals that TubB1 has an accelerated evolutionary rate probably due to a release of functional constraints in connexion with a specialization of microtubular structures in rhodophytes. It further indicates that isoform diversity and functional differentiation of tubulins in eukaryotic cells may be controlled by independent selective constraints. TubB1 has a short spliceosomal intron at its 5' end which seems to be a characteristic feature of nuclear protein-coding genes from rhodophytes. The splice junctions of the four known rhodophyte introns comply well with the corresponding consensus sequences of higher plants in agreement with previous suggestions from phylogenetic inference that red algae and green plants may be sister groups. The paucity and asymmetrical location of introns in rhodophyte genes can be explained by differential intron loss due to conversion of genes by homologous recombination with cDNAs corresponding to reverse transcribed mRNAs or partially spliced pre-mRNAs, respectively. The identification of an intron containing TubB1 cDNA in C. crispus confirms that pre-mRNAs can escape both splicing and degradation in the nucleus prior to transport into the cytoplasm. Differential Southern hybridizations under non-stringent conditions with homologous and heterologous probes suggest that C. crispus contains a second degenerate beta-tubulin gene (or pseudogene?) which, however, is only distantly related to TubB1 as it is to the more conserved homologues of other organisms."xsd:string |
| http://purl.uniprot.org/citations/7599316 | http://purl.org/dc/terms/identifier | "doi:10.1007/bf00020250"xsd:string |
| http://purl.uniprot.org/citations/7599316 | http://purl.org/dc/terms/identifier | "doi:10.1007/bf00020250"xsd:string |
| http://purl.uniprot.org/citations/7599316 | http://purl.uniprot.org/core/author | "Brandt U."xsd:string |
| http://purl.uniprot.org/citations/7599316 | http://purl.uniprot.org/core/author | "Brandt U."xsd:string |
| http://purl.uniprot.org/citations/7599316 | http://purl.uniprot.org/core/author | "Cerff R."xsd:string |
| http://purl.uniprot.org/citations/7599316 | http://purl.uniprot.org/core/author | "Cerff R."xsd:string |
| http://purl.uniprot.org/citations/7599316 | http://purl.uniprot.org/core/author | "Liaud M.-F."xsd:string |
| http://purl.uniprot.org/citations/7599316 | http://purl.uniprot.org/core/author | "Liaud M.-F."xsd:string |
| http://purl.uniprot.org/citations/7599316 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7599316 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7599316 | http://purl.uniprot.org/core/name | "Plant Mol. Biol."xsd:string |
| http://purl.uniprot.org/citations/7599316 | http://purl.uniprot.org/core/name | "Plant Mol. Biol."xsd:string |
| http://purl.uniprot.org/citations/7599316 | http://purl.uniprot.org/core/pages | "313-325"xsd:string |
| http://purl.uniprot.org/citations/7599316 | http://purl.uniprot.org/core/pages | "313-325"xsd:string |
| http://purl.uniprot.org/citations/7599316 | http://purl.uniprot.org/core/title | "The marine red alga Chondrus crispus has a highly divergent beta-tubulin gene with a characteristic 5' intron: functional and evolutionary implications."xsd:string |
| http://purl.uniprot.org/citations/7599316 | http://purl.uniprot.org/core/title | "The marine red alga Chondrus crispus has a highly divergent beta-tubulin gene with a characteristic 5' intron: functional and evolutionary implications."xsd:string |
| http://purl.uniprot.org/citations/7599316 | http://purl.uniprot.org/core/volume | "28"xsd:string |
| http://purl.uniprot.org/citations/7599316 | http://purl.uniprot.org/core/volume | "28"xsd:string |
| http://purl.uniprot.org/citations/7599316 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7599316 |
| http://purl.uniprot.org/citations/7599316 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7599316 |
| http://purl.uniprot.org/citations/7599316 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7599316 |
| http://purl.uniprot.org/citations/7599316 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7599316 |