| http://purl.uniprot.org/citations/7605356 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7605356 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7605356 | http://www.w3.org/2000/01/rdf-schema#comment | "The present report describes a competitive enzyme immunoassay for rabbit apolipoprotein A-IV (apo A-IV). This assay was applied to the determination of its concentration and distribution in sera from normolipidemic and hyperlipidemic rabbits. The assay was sufficiently sensitive to study this 42-kDa protein in lipoproteins fractionated from 200 microliters of serum by FPLC gel filtration. In normolipidemic sera (n = 8), apo A-IV concentration was 5.32 +/-0.76 mg/dl. A diet rich in cholesterol (0.5%), which induced an 18-fold increase in serum cholesterol, did not significantly alter apo A-IV concentration (6.65 +/-1.52 mg/dl, n = 8). By contrast, genetically induced hypercholesterolemia (Watanabe heritable hyperlipidemia, WHHL mutation) caused a significantly reduced level of apo A-IV (3.8 +/-1.14 mg/dl, n = 7). In each of the groups studied, apo A-IV was distributed in two distinct pools; a high-density lipoprotein-(HDL) associated pool and a lipoprotein-free pool. However, compared to normal, the distribution of apo A-IV in WHHL rabbit sera was shifted towards the lipoprotein-free pool. Consistent with previously reported observations on apo A-I, these results are compatible with the hypothesis of an impaired reverse transport of cholesterol in WHHL rabbits, an animal model for familial hypercholesterolemia."xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://purl.org/dc/terms/identifier | "doi:10.1016/0021-9150(94)05444-N"xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://purl.org/dc/terms/identifier | "doi:10.1016/0021-9150(94)05444-n"xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://purl.uniprot.org/core/author | "Nomura S."xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://purl.uniprot.org/core/author | "Nomura S."xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://purl.uniprot.org/core/author | "Yamamoto A."xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://purl.uniprot.org/core/author | "Yamamoto A."xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://purl.uniprot.org/core/author | "Yamamura T."xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://purl.uniprot.org/core/author | "Yamamura T."xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://purl.uniprot.org/core/author | "Mezdour H."xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://purl.uniprot.org/core/author | "Mezdour H."xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7605356 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7605356 | http://purl.uniprot.org/core/name | "Atherosclerosis"xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://purl.uniprot.org/core/name | "Atherosclerosis"xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://purl.uniprot.org/core/pages | "171-178"xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://purl.uniprot.org/core/pages | "171-178"xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://purl.uniprot.org/core/title | "Genetic but not diet-induced hypercholesterolemia causes low apolipoprotein A-IV level in rabbit sera."xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://purl.uniprot.org/core/title | "Genetic but not diet-induced hypercholesterolemia causes low apolipoprotein A-IV level in rabbit sera."xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://purl.uniprot.org/core/volume | "113"xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://purl.uniprot.org/core/volume | "113"xsd:string |
| http://purl.uniprot.org/citations/7605356 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7605356 |
| http://purl.uniprot.org/citations/7605356 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7605356 |