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http://purl.uniprot.org/citations/7605908 | http://www.w3.org/2000/01/rdf-schema#comment | "Homozygote wobbler mice develop motoneurone degeneration. Throughout development the expression of choline acetyltransferase, of trkC receptor and F3 adhesion molecule genes is similar in wobbler and wild-type spinal cord. Acetylcholinesterase mRNA level instead is decreased to about 50% with respect to wild-type values in one forth of P5 and P10 wobbler progeny, putative wr/wr individuals; at P21 its expression is equally highly reduced in known homozygotes and it is reduced to 35% of normal values in about one half of the progeny, putative heterozygotes. Thus, similarly to medium neurofilament gene over-expression, reduced acetylcholinesterase gene expression is an early molecular marker for the wobbler mutation before onset of the illness."xsd:string |
http://purl.uniprot.org/citations/7605908 | http://purl.org/dc/terms/identifier | "doi:10.1097/00001756-199503000-00003"xsd:string |
http://purl.uniprot.org/citations/7605908 | http://purl.uniprot.org/core/author | "Hansen C.T."xsd:string |
http://purl.uniprot.org/citations/7605908 | http://purl.uniprot.org/core/author | "Pernas-Alonso R."xsd:string |
http://purl.uniprot.org/citations/7605908 | http://purl.uniprot.org/core/author | "Barker J.L."xsd:string |
http://purl.uniprot.org/citations/7605908 | http://purl.uniprot.org/core/author | "Schaffner A.E."xsd:string |
http://purl.uniprot.org/citations/7605908 | http://purl.uniprot.org/core/author | "di Porzio U."xsd:string |
http://purl.uniprot.org/citations/7605908 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
http://purl.uniprot.org/citations/7605908 | http://purl.uniprot.org/core/name | "Neuroreport"xsd:string |
http://purl.uniprot.org/citations/7605908 | http://purl.uniprot.org/core/pages | "597-600"xsd:string |
http://purl.uniprot.org/citations/7605908 | http://purl.uniprot.org/core/title | "Acetylcholine esterase and peripherin mRNA level decrease in wobbler mouse."xsd:string |
http://purl.uniprot.org/citations/7605908 | http://purl.uniprot.org/core/volume | "6"xsd:string |
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