| http://purl.uniprot.org/citations/7607214 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7607214 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7607214 | http://www.w3.org/2000/01/rdf-schema#comment | "We have revealed and characterised two nucleic-acid-binding proteins, termed PCBP-1 (M(r) 37,525, pI 7.07) and PCBP-2 (M(r) 38,579, pI 6.76), that together with heterogeneous ribonucleoparticle (hnRNP)-K correspond to the major cellular poly(rC)-binding proteins. mRNA for both PCBPs were detected in all the human tissues analysed. Both proteins contain three K-homologous (KH) domains which share similarity with other KH domain proteins, including the fragile-X protein FMR1, and which are positioned as in hnRNP-K and nova, i.e. with two closely spaced domains at the N-terminus and one at the C-terminus. PCBPs do not contain RGG boxes or any other known nucleic-acid-binding motifs. Expression in the vaccinia virus system showed that both proteins are post-translationally modified in vivo, a fact that was confirmed by [32P]orthophosphate labelling. Northwestern-blot analysis showed that the non-phosphorylated forms bind tenaciously to poly(rC) in vitro, while significantly less binding was observed for the phosphorylated variants. Escherichia coli expressed proteins also bound poly(rG), albeit at a lower level. In addition, PCBP-2 bound poly(rU), whereas very little binding to poly(rA) was observed for both proteins."xsd:string |
| http://purl.uniprot.org/citations/7607214 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1432-1033.1995.tb20581.x"xsd:string |
| http://purl.uniprot.org/citations/7607214 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1432-1033.1995.tb20581.x"xsd:string |
| http://purl.uniprot.org/citations/7607214 | http://purl.uniprot.org/core/author | "Celis J.E."xsd:string |
| http://purl.uniprot.org/citations/7607214 | http://purl.uniprot.org/core/author | "Celis J.E."xsd:string |
| http://purl.uniprot.org/citations/7607214 | http://purl.uniprot.org/core/author | "Leffers H."xsd:string |
| http://purl.uniprot.org/citations/7607214 | http://purl.uniprot.org/core/author | "Leffers H."xsd:string |
| http://purl.uniprot.org/citations/7607214 | http://purl.uniprot.org/core/author | "Dejgaard K."xsd:string |
| http://purl.uniprot.org/citations/7607214 | http://purl.uniprot.org/core/author | "Dejgaard K."xsd:string |
| http://purl.uniprot.org/citations/7607214 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7607214 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7607214 | http://purl.uniprot.org/core/name | "Eur. J. Biochem."xsd:string |
| http://purl.uniprot.org/citations/7607214 | http://purl.uniprot.org/core/name | "Eur. J. Biochem."xsd:string |
| http://purl.uniprot.org/citations/7607214 | http://purl.uniprot.org/core/pages | "447-453"xsd:string |
| http://purl.uniprot.org/citations/7607214 | http://purl.uniprot.org/core/pages | "447-453"xsd:string |
| http://purl.uniprot.org/citations/7607214 | http://purl.uniprot.org/core/title | "Characterisation of two major cellular poly(rC)-binding human proteins, each containing three K-homologous (KH) domains."xsd:string |
| http://purl.uniprot.org/citations/7607214 | http://purl.uniprot.org/core/title | "Characterisation of two major cellular poly(rC)-binding human proteins, each containing three K-homologous (KH) domains."xsd:string |
| http://purl.uniprot.org/citations/7607214 | http://purl.uniprot.org/core/volume | "230"xsd:string |
| http://purl.uniprot.org/citations/7607214 | http://purl.uniprot.org/core/volume | "230"xsd:string |
| http://purl.uniprot.org/citations/7607214 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7607214 |
| http://purl.uniprot.org/citations/7607214 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7607214 |
| http://purl.uniprot.org/citations/7607214 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7607214 |
| http://purl.uniprot.org/citations/7607214 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7607214 |