| http://purl.uniprot.org/citations/7607547 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7607547 | http://www.w3.org/2000/01/rdf-schema#comment | "The recognition sequence (CIB) of collagen intron-binding factor I (CIBF-I) loosely resembles the consensus octamer-binding motif (OCT). In the present study we investigate whether CIBF-I is actually the OCT-binding protein, Oct-1. Electrophoretic mobility-shift assays (EMSA) demonstrate that a consensus OCT motif effectively competes for CIBF-I binding. CIBF-I and Oct-1 complexes display similar EMSA characteristics, and both factors are detected in nuclear extracts of five different cell types. In addition, pre-incubation of nuclear extracts with antiserum directed against the POU domain of Oct-1 inhibits CIBF-I complex formation. Finally, DNA transfection experiments demonstrate that a single copy of the CIB site is sufficient to stimulate transcription from the SV40 early promoter in NIH 3T3 cells. These results suggest that CIBF-I is the ubiquitously distributed OCT-binding protein, Oct-1, and represent the first report that an octamer-binding protein contributes to the transcriptional activity of a collagen-encoding gene."xsd:string |
| http://purl.uniprot.org/citations/7607547 | http://purl.org/dc/terms/identifier | "doi:10.1016/0378-1119(95)00157-2"xsd:string |
| http://purl.uniprot.org/citations/7607547 | http://purl.uniprot.org/core/author | "Freytag S.O."xsd:string |
| http://purl.uniprot.org/citations/7607547 | http://purl.uniprot.org/core/author | "Pogulis R.J."xsd:string |
| http://purl.uniprot.org/citations/7607547 | http://purl.uniprot.org/core/author | "Geddes T.J."xsd:string |
| http://purl.uniprot.org/citations/7607547 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7607547 | http://purl.uniprot.org/core/name | "Gene"xsd:string |
| http://purl.uniprot.org/citations/7607547 | http://purl.uniprot.org/core/pages | "231-235"xsd:string |
| http://purl.uniprot.org/citations/7607547 | http://purl.uniprot.org/core/title | "Murine collagen intron-binding factor I (CIBF-I) is the same protein as transcription factor Oct-1."xsd:string |
| http://purl.uniprot.org/citations/7607547 | http://purl.uniprot.org/core/volume | "158"xsd:string |
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