| http://purl.uniprot.org/citations/7609734 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7609734 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7609734 | http://www.w3.org/2000/01/rdf-schema#comment | "Using a novel subtractive hybridization approach, we have identified a set of cDNA clones whose expression is downregulated in the thymus by cyclosporin-A (CsA). A number of regulated genes were identified, but the major focus of this report is the clone termed CsA-19. In the adult mouse, CsA-19 is expressed at high levels in lymphoid organs, particularly in secondary lymphoid organs such as lymph node and spleen. CsA-19 expression was also found to be regulated in the brain and liver during mouse development. The full length sequences of the murine and human CsA-19 cDNAs have been determined. Both are 700 nucleotides in length and encode a predicted product of 217 amino acids. Comparison of the full length cDNA sequences of murine and human CsA-19 reveal that they are greater than 91% conserved. At the predicted amino acid level the homology is even greater, with only two amino acid differences in 217 residues (99% identity). The high degree of homology between murine and human CsA-19 indicates that has there been strong evolutionary pressure to conserve the amino acid sequence of CsA-19, and suggests that CsA-19 may play a critical role both during embryogenesis and in mature lymphoid cells."xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.org/dc/terms/identifier | "doi:10.1016/0161-5890(95)00032-a"xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.org/dc/terms/identifier | "doi:10.1016/0161-5890(95)00032-a"xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/author | "Williams J."xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/author | "Williams J."xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/author | "Katerelos M."xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/author | "Katerelos M."xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/author | "Power D."xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/author | "Power D."xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/author | "D'Apice A."xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/author | "D'Apice A."xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/author | "Fisicaro N."xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/author | "Fisicaro N."xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/author | "Pearse M."xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/author | "Pearse M."xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/name | "Mol. Immunol."xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/name | "Mol. Immunol."xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/pages | "565-572"xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/pages | "565-572"xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/title | "Identification of genes downregulated in the thymus by cyclosporin-A: preliminary characterization of clone CSA-19."xsd:string |
| http://purl.uniprot.org/citations/7609734 | http://purl.uniprot.org/core/title | "Identification of genes downregulated in the thymus by cyclosporin-A: preliminary characterization of clone CSA-19."xsd:string |