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http://purl.uniprot.org/citations/7618084http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7618084http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7618084http://www.w3.org/2000/01/rdf-schema#comment"Gene targeting was used to create a null allele at the epidermal growth factor receptor locus (Egfr). The phenotype was dependent on genetic background. EGFR deficiency on a CF-1 background resulted in peri-implantation death due to degeneration of the inner cell mass. On a 129/Sv background, homozygous mutants died at mid-gestation due to placental defects; on a CD-1 background, the mutants lived for up to 3 weeks and showed abnormalities in skin, kidney, brain, liver, and gastrointestinal tract. The multiple abnormalities associated with EGFR deficiency indicate that the receptor is involved in a wide range of cellular activities."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.org/dc/terms/identifier"doi:10.1126/science.7618084"xsd:string
http://purl.uniprot.org/citations/7618084http://purl.org/dc/terms/identifier"doi:10.1126/science.7618084"xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"Harris R.C."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"Harris R.C."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"Herrup K."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"Herrup K."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"Yee D."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"Yee D."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"Dlugosz A.A."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"Dlugosz A.A."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"Hansen L.A."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"Hansen L.A."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"LaMantia C."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"LaMantia C."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"Lichti U."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"Lichti U."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"Mourton T."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"Mourton T."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"Tennenbaum T."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"Tennenbaum T."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"Threadgill D.W."xsd:string
http://purl.uniprot.org/citations/7618084http://purl.uniprot.org/core/author"Threadgill D.W."xsd:string