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http://purl.uniprot.org/citations/7634099http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7634099http://www.w3.org/2000/01/rdf-schema#comment"Pertussis toxin is an exotoxin from the bacterium Bordetella pertussis which is important the pathogenesis of whooping cough and the generation of a protective immune response. The diverse biological activities of the toxin depend on its ability to recognize carbohydrate-containing receptors on a wide variety of eukaryotic cells. We present here the crystal structure of pertussis toxin complexed with a soluble oligosaccharide from transferrin. Binding sites for the terminal sialic acid-galactose moiety are revealed on both subunits S2 and S3 of the B-oligomer. Identification of amino acid residues involved in receptor binding will improve the design of genetically inactivated toxins for use in new acellular whooping cough vaccines."xsd:string
http://purl.uniprot.org/citations/7634099http://purl.org/dc/terms/identifier"doi:10.1038/nsb0994-591"xsd:string
http://purl.uniprot.org/citations/7634099http://purl.uniprot.org/core/author"Read R.J."xsd:string
http://purl.uniprot.org/citations/7634099http://purl.uniprot.org/core/author"Klein M.H."xsd:string
http://purl.uniprot.org/citations/7634099http://purl.uniprot.org/core/author"Stein P.E."xsd:string
http://purl.uniprot.org/citations/7634099http://purl.uniprot.org/core/author"Boodhoo A."xsd:string
http://purl.uniprot.org/citations/7634099http://purl.uniprot.org/core/author"Armstrong G.D."xsd:string
http://purl.uniprot.org/citations/7634099http://purl.uniprot.org/core/author"Cockle S.A."xsd:string
http://purl.uniprot.org/citations/7634099http://purl.uniprot.org/core/author"Heerze L.D."xsd:string
http://purl.uniprot.org/citations/7634099http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/7634099http://purl.uniprot.org/core/name"Nat Struct Biol"xsd:string
http://purl.uniprot.org/citations/7634099http://purl.uniprot.org/core/pages"591-596"xsd:string
http://purl.uniprot.org/citations/7634099http://purl.uniprot.org/core/title"Structure of a pertussis toxin-sugar complex as a model for receptor binding."xsd:string
http://purl.uniprot.org/citations/7634099http://purl.uniprot.org/core/volume"1"xsd:string
http://purl.uniprot.org/citations/7634099http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/7634099
http://purl.uniprot.org/citations/7634099http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/7634099
http://purl.uniprot.org/uniprot/#_P0A3R5-mappedCitation-7634099http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/7634099
http://purl.uniprot.org/uniprot/#_P04977-mappedCitation-7634099http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/7634099
http://purl.uniprot.org/uniprot/#_P04978-mappedCitation-7634099http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/7634099
http://purl.uniprot.org/uniprot/#_P04979-mappedCitation-7634099http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/7634099
http://purl.uniprot.org/uniprot/#_P04981-mappedCitation-7634099http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/7634099
http://purl.uniprot.org/uniprot/P0A3R5http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/7634099
http://purl.uniprot.org/uniprot/P04979http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/7634099
http://purl.uniprot.org/uniprot/P04978http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/7634099