| http://purl.uniprot.org/citations/7642639 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7642639 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7642639 | http://www.w3.org/2000/01/rdf-schema#comment | "Mitosin is a novel 350-kDa nuclear phosphoprotein that dramatically relocates from the evenly nuclear distribution in S phase to the centromere/kinetochore and mitotic apparatus in M phase. The dynamic relocalization of mitosin is accompanied by the phosphorylation of itself, suggesting that mitosin plays a role in mitotic progression. The molecular basis of nuclear localization and targeting of mitosin to the centromere/kinetochore were characterized using a set of epitope-tagged deletion mutants. The data indicate that the extreme C terminus (amino acids 2,487-3,113) of mitosin has both an independent centromere/kinetochore targeting domain and an unusually spaced bipartite nuclear localization signal. Moreover, the same centromere/kinetochore targeting domain was shown to be essential for the ability of mitosin to bind to itself or other putative mitosin-associated proteins through use of the yeast two-hybrid system. These results suggest that the C terminus of the mitosin is essential for its role in influencing cell cycle progression."xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.270.33.19545"xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.270.33.19545"xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/author | "Lee W.-H."xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/author | "Lee W.-H."xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/author | "Zhu X."xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/author | "Zhu X."xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/author | "He D."xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/author | "He D."xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/author | "Brinkley W.R."xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/author | "Brinkley W.R."xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/author | "Mancini M.A."xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/author | "Mancini M.A."xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/author | "Chang K.-H."xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/author | "Chang K.-H."xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/pages | "19545-19550"xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/pages | "19545-19550"xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/title | "The C-terminus of mitosin is essential for its nuclear localization, centromere/kinetochore targeting, and dimerization."xsd:string |
| http://purl.uniprot.org/citations/7642639 | http://purl.uniprot.org/core/title | "The C-terminus of mitosin is essential for its nuclear localization, centromere/kinetochore targeting, and dimerization."xsd:string |