| http://purl.uniprot.org/citations/7660130 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7660130 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7660130 | http://www.w3.org/2000/01/rdf-schema#comment | "Germ-line mutations of the von Hippel-Lindau tumor suppressor gene (VHL) predispose individuals to a variety of human tumors, and somatic mutations of this gene have been identified in sporadic renal cell carcinomas and cerebellar hemangioblastomas. Two transcriptional elongation factors, Elongin B and C, were shown to bind in vitro and in vivo to a short, colinear region of the VHL protein (pVHL) that is frequently mutated in human tumors. A peptide replica of this region inhibited binding of pVHL to Elongin B and C whereas a point-mutant derivative, corresponding to a naturally occurring VHL missense mutation, had no effect. These results suggest that the tumor suppression function of pVHL may be linked to its ability to bind to Elongin B and C."xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.7660130"xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.7660130"xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://purl.uniprot.org/core/author | "DeCaprio J.A."xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://purl.uniprot.org/core/author | "DeCaprio J.A."xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://purl.uniprot.org/core/author | "Kaelin W.G. Jr."xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://purl.uniprot.org/core/author | "Kaelin W.G. Jr."xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://purl.uniprot.org/core/author | "Iliopoulos O."xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://purl.uniprot.org/core/author | "Iliopoulos O."xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://purl.uniprot.org/core/author | "Kibel A."xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://purl.uniprot.org/core/author | "Kibel A."xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7660130 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7660130 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://purl.uniprot.org/core/pages | "1444-1446"xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://purl.uniprot.org/core/pages | "1444-1446"xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://purl.uniprot.org/core/title | "Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C."xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://purl.uniprot.org/core/title | "Binding of the von Hippel-Lindau tumor suppressor protein to Elongin B and C."xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://purl.uniprot.org/core/volume | "269"xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://purl.uniprot.org/core/volume | "269"xsd:string |
| http://purl.uniprot.org/citations/7660130 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7660130 |
| http://purl.uniprot.org/citations/7660130 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7660130 |