| http://purl.uniprot.org/citations/7664883 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7664883 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7664883 | http://www.w3.org/2000/01/rdf-schema#comment | "The association of cyclosporin A (CsA) immunosuppression with inhibition of transcription factor-dependent lymphokine gene activation formed the basis of our decision to investigate nuclear-associated Cyp isoforms. Immunofluorescence microscopy of mouse macrophages cell line with a monoclonal antibody mAb7F1 raised against CypA shows a co-localisation of CypA in the nucleus and in the cytosol. Nuclear CypA binds to DNA in a zinc ion-dependent manner, in contrast to recombinant CypB. Peptidyl-prolyl cisltrans isomerase (PPIase) activity of nuclear CypA is inhibited by zinc ions. The zinc inhibited CypA does not bind cyclosporin A (CsA). We suggest that nuclear Cyp in complex with zinc ions recognizes DNA sequences and is involved in transcription modulating processes."xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.org/dc/terms/identifier | "doi:10.1016/0014-5793(95)00815-q"xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.org/dc/terms/identifier | "doi:10.1016/0014-5793(95)00815-q"xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/author | "Bang H."xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/author | "Bang H."xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/author | "Brune K."xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/author | "Brune K."xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/author | "Schmidtchen R."xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/author | "Schmidtchen R."xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/author | "Krummrei U."xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/author | "Krummrei U."xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/author | "Bang R."xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/author | "Bang R."xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/pages | "47-51"xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/pages | "47-51"xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/title | "Cyclophilin-A is a zinc-dependent DNA binding protein in macrophages."xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/title | "Cyclophilin-A is a zinc-dependent DNA binding protein in macrophages."xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/volume | "371"xsd:string |
| http://purl.uniprot.org/citations/7664883 | http://purl.uniprot.org/core/volume | "371"xsd:string |