http://purl.uniprot.org/citations/7671308 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/7671308 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/7671308 | http://www.w3.org/2000/01/rdf-schema#comment | "While significant progress has been made in understanding the molecular events underlying the early specification of the antero-posterior and dorso-ventral axes, little information is available regarding the cellular or molecular basis for left-right (LR) differences in animal morphogenesis. We describe the expression patterns of three genes involved in LR determination in chick embryos: activin receptor IIa, Sonic hedgehog (Shh), and cNR-1 (related to the mouse gene nodal). These genes are expressed asymmetrically during and after gastrulation and regulate the expression of one another in a sequential pathway. Moreover, manipulation of the sidedness of either activin protein or Shh expression alters heart situs. Together, these observations identify a cascade of molecular asymmetry in that determines morphological LR asymmetry in the chick embryo."xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.org/dc/terms/identifier | "doi:10.1016/0092-8674(95)90477-8"xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.org/dc/terms/identifier | "doi:10.1016/0092-8674(95)90477-8"xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/author | "Johnson R.L."xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/author | "Johnson R.L."xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/author | "Levin M."xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/author | "Levin M."xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/author | "Stern C.D."xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/author | "Stern C.D."xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/author | "Kuehn M."xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/author | "Kuehn M."xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/author | "Tabin C."xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/author | "Tabin C."xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/pages | "803-814"xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/pages | "803-814"xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/title | "A molecular pathway determining left-right asymmetry in chick embryogenesis."xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/title | "A molecular pathway determining left-right asymmetry in chick embryogenesis."xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/volume | "82"xsd:string |
http://purl.uniprot.org/citations/7671308 | http://purl.uniprot.org/core/volume | "82"xsd:string |