| http://purl.uniprot.org/citations/7685113 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7685113 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7685113 | http://www.w3.org/2000/01/rdf-schema#comment | "A cDNA encoding a full-length N-methyl-D-aspartate (NMDA) receptor subunit 1, hNR1, was isolated from a human brain cDNA library. The hNR1 cDNA encodes an open reading frame of approximately 2.7 kb that shares high homology with the rat brain NMDA receptor subunit 1 and the mouse zeta 1 subunit. The hNR1 sequence, however, diverges from the rodent and murine homologs near the C terminus, suggesting that they represent alternatively spliced messages of the same gene. Oocytes injected with cRNA synthesized from the hNR1 cDNA express glutamate and NMDA-activated currents in the presence of glycine. Currents are blocked by the NMDA-receptor-specific antagonists 2-amino-5-phosphovaleric acid and 7-chlorokynurenate, and the open channel blockers MK-801 and phencyclidine, by Mg2+ ions in a voltage-dependent manner, and by Zn2+. Expressed hNR1 homomeric receptor channels exhibit the high Ca2+ permeability characteristic of neuronal NMDA receptors. Therefore, the cDNA clone hNR1 codes for a human brain NMDA receptor subunit cognate to the rodent and murine brain NR1 subunits."xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.90.11.5057"xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.90.11.5057"xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://purl.uniprot.org/core/author | "Sun W."xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://purl.uniprot.org/core/author | "Sun W."xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://purl.uniprot.org/core/author | "Montal M."xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://purl.uniprot.org/core/author | "Montal M."xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://purl.uniprot.org/core/author | "Ferrer-Montiel A.V."xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://purl.uniprot.org/core/author | "Ferrer-Montiel A.V."xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://purl.uniprot.org/core/author | "Planells-Cases R."xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://purl.uniprot.org/core/author | "Planells-Cases R."xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/7685113 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/7685113 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://purl.uniprot.org/core/pages | "5057-5061"xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://purl.uniprot.org/core/pages | "5057-5061"xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://purl.uniprot.org/core/title | "Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain."xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://purl.uniprot.org/core/title | "Molecular cloning, functional expression, and pharmacological characterization of an N-methyl-D-aspartate receptor subunit from human brain."xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://purl.uniprot.org/core/volume | "90"xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://purl.uniprot.org/core/volume | "90"xsd:string |
| http://purl.uniprot.org/citations/7685113 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7685113 |
| http://purl.uniprot.org/citations/7685113 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7685113 |