| http://purl.uniprot.org/citations/7711835 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7711835 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7711835 | http://www.w3.org/2000/01/rdf-schema#comment | "The expression of Na,K-ATPase isoforms was investigated in human skeletal muscle membranes isolated by subcellular fractionation. The alpha 1, alpha 2, alpha 3 and beta 1 subunits were detectable in membranes prepared from the human soleus muscle. The alpha 1 subunit was largely detected in a fraction enriched with plasma membranes (PM), its abundance in an intracellular membrane fraction (IM) accounted for only 4% of that in the PM fraction. No alpha 1 subunits were detected in membranes of sarcoplasmic reticulum (SR) origin. The PM and IM fractions were enriched with alpha 2 subunits which were less abundant in the SR-enriched fraction. The abundance of alpha 2 molecules within the IM fraction was about 75% of that in the PM fraction when the total protein content for the two fractions was taken into account. Immunocytochemical studies confirmed the localization of the alpha 1 subunit to the muscle cell surface. The alpha 2 subunit was also found to be present in the cell surface but the observation that alpha 2 immunofluorescence was diffusely dispersed throughout the muscle fibre indicated that it was also present intracellularly, consistent with its biochemical localization in the PM and IM membrane fractions. The alpha 3 subunit was detected largely in the PM fraction but the lack of good antibodies to this isoform precluded an analysis of its immunocytochemical localization. The beta 1 subunit was enriched in the PM fraction but was also detected to a modest extent in the IM.(ABSTRACT TRUNCATED AT 250 WORDS)"xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.org/dc/terms/identifier | "doi:10.3109/09687689409160435"xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.org/dc/terms/identifier | "doi:10.3109/09687689409160435"xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/author | "Ahmed A."xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/author | "Ahmed A."xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/author | "Hundal H.S."xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/author | "Hundal H.S."xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/author | "Klip A."xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/author | "Klip A."xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/author | "Darakhshan F."xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/author | "Darakhshan F."xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/author | "Maxwell D.L."xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/author | "Maxwell D.L."xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/author | "Mitsumoto Y."xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/author | "Mitsumoto Y."xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/name | "Mol. Membr. Biol."xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/name | "Mol. Membr. Biol."xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/pages | "255-262"xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/pages | "255-262"xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/title | "Subcellular distribution and immunocytochemical localization of Na,K-ATPase subunit isoforms in human skeletal muscle."xsd:string |
| http://purl.uniprot.org/citations/7711835 | http://purl.uniprot.org/core/title | "Subcellular distribution and immunocytochemical localization of Na,K-ATPase subunit isoforms in human skeletal muscle."xsd:string |