| http://purl.uniprot.org/citations/7713500 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7713500 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7713500 | http://www.w3.org/2000/01/rdf-schema#comment | "8-Oxo-dGTP (8-oxo-7,8-dihydrodeoxyguanosine triphosphate) is produced by active oxygen species in the nucleotide pool of the cell and can be incorporated into cellular DNA. Human cells contain enzyme activity that hydrolyzes 8-oxo-dGTP to 8-oxo-dGMP, thereby preventing occurrence of mutations, caused by misincorporation. When the cDNA for human 8-oxo-dGTPase was expressed in Escherichia coli mutT-mutant cells devoid of self 8-oxo-dGTPase activity, the elevated level of spontaneous A:T to C:G mutation frequency reverted to normal. We isolated the genomic sequence encoding the enzyme and named the gene MTH1 (for mutT human homologue). This gene is composed of at least 4 exons, spans approximately 9 kb, and is located on human chromosome 7p22."xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.org/dc/terms/identifier | "doi:10.1006/geno.1994.1657"xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.org/dc/terms/identifier | "doi:10.1006/geno.1994.1657"xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/author | "Nakabeppu Y."xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/author | "Nakabeppu Y."xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/author | "Sekiguchi M."xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/author | "Sekiguchi M."xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/author | "Furuichi M."xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/author | "Furuichi M."xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/author | "Oda H."xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/author | "Oda H."xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/author | "Tajiri T."xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/author | "Tajiri T."xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/author | "Tsuzuki T."xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/author | "Tsuzuki T."xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/author | "Yoshida M.C."xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/author | "Yoshida M.C."xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/name | "Genomics"xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/name | "Genomics"xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/pages | "485-490"xsd:string |
| http://purl.uniprot.org/citations/7713500 | http://purl.uniprot.org/core/pages | "485-490"xsd:string |