| http://purl.uniprot.org/citations/7746155 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7746155 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7746155 | http://www.w3.org/2000/01/rdf-schema#comment | "TIP1 is the first known cold-shock- and heat-shock-induced gene in Saccharomyces cerevislae. Here it is demonstrated that a TIP1 homologue, TIR1, which had been previously cloned as SRP1 (serine-rich protein), is strongly induced by a downshift in growth temperature from 30 to 10 degrees C. We further cloned TIR2, which is transcribed at a low basal level but is increased strongly by cold shock and, to a lesser extent, by heat shock. The predicted protein sequence of TIR2 demonstrates remarkable homology to TIR1 (72.2%) and is also homologous with TIP1 (49%). TIP1, TIR1 and TIR2 are rich in both serine and alanine residues and each contains serine-rich tandem repeats. The proteins contain putative N-terminal signal peptides as well as hydrophobic C-terminal sequences, indicating that the proteins may be membrane bound. The predicted protein sequences are also consistent with extensive O-mannosylation as well as glycosyl-phosphatidyl inositol (GPI) membrane anchoring. Cell fractionation analysis as well as studies using a yeast strain that is conditionally deficient in glycosylation demonstrate that TIP1 is a heavily modified membrane-associated protein. Single, double combinations and triple mutants were created and none demonstrated any obvious phenotype, indicating that this family of genes is not essential for normal growth."xsd:string |
| http://purl.uniprot.org/citations/7746155 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1365-2958.1995.tb02248.x"xsd:string |
| http://purl.uniprot.org/citations/7746155 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1365-2958.1995.tb02248.x"xsd:string |
| http://purl.uniprot.org/citations/7746155 | http://purl.uniprot.org/core/author | "Inouye M."xsd:string |
| http://purl.uniprot.org/citations/7746155 | http://purl.uniprot.org/core/author | "Inouye M."xsd:string |
| http://purl.uniprot.org/citations/7746155 | http://purl.uniprot.org/core/author | "Kondo K."xsd:string |
| http://purl.uniprot.org/citations/7746155 | http://purl.uniprot.org/core/author | "Kondo K."xsd:string |
| http://purl.uniprot.org/citations/7746155 | http://purl.uniprot.org/core/author | "Kowalski L.R.Z."xsd:string |
| http://purl.uniprot.org/citations/7746155 | http://purl.uniprot.org/core/author | "Kowalski L.R.Z."xsd:string |
| http://purl.uniprot.org/citations/7746155 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7746155 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7746155 | http://purl.uniprot.org/core/name | "Mol. Microbiol."xsd:string |
| http://purl.uniprot.org/citations/7746155 | http://purl.uniprot.org/core/name | "Mol. Microbiol."xsd:string |
| http://purl.uniprot.org/citations/7746155 | http://purl.uniprot.org/core/pages | "341-353"xsd:string |
| http://purl.uniprot.org/citations/7746155 | http://purl.uniprot.org/core/pages | "341-353"xsd:string |
| http://purl.uniprot.org/citations/7746155 | http://purl.uniprot.org/core/title | "Cold-shock induction of a family of TIP1-related proteins associated with the membrane in Saccharomyces cerevisiae."xsd:string |
| http://purl.uniprot.org/citations/7746155 | http://purl.uniprot.org/core/title | "Cold-shock induction of a family of TIP1-related proteins associated with the membrane in Saccharomyces cerevisiae."xsd:string |
| http://purl.uniprot.org/citations/7746155 | http://purl.uniprot.org/core/volume | "15"xsd:string |
| http://purl.uniprot.org/citations/7746155 | http://purl.uniprot.org/core/volume | "15"xsd:string |
| http://purl.uniprot.org/citations/7746155 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7746155 |
| http://purl.uniprot.org/citations/7746155 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7746155 |
| http://purl.uniprot.org/citations/7746155 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7746155 |
| http://purl.uniprot.org/citations/7746155 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7746155 |