| http://purl.uniprot.org/citations/7755634 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7755634 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7755634 | http://www.w3.org/2000/01/rdf-schema#comment | "The human histidyl-tRNA synthetase (HRS) gene encodes an enzyme that catalyzes the esterification of histidine to its cognate tRNA as an early step in protein biosynthesis. Previous reports have described a bidirectional promoter element which coordinates the transcription of both HRS and an unknown mRNA whose gene is oriented in a head-to-head configuration with HRS. We have isolated and characterized a human genomic DNA clone that encodes portions of these oppositely transcribed mRNAs and a putatively full-length cDNA clone (HO3) corresponding to the gene mapping immediately 5' of HRS. The largest open reading frame within HO3 (1518 bp) shares approximately 75% nucleotide sequence identity with human HRS (1527 bp) and predicts a polypeptide with extensive amino acid sequence homology with the HRS protein (72%). Moreover, amino acid sequence motifs characteristic of class II aminoacyl-tRNA synthetases are conserved within HO3. Despite their similarity, HRS and HO3 have divergent amino-terminal domains which correspond to the first two exons of each gene. RNA blot analysis revealed that HRS (2.0 kb) and HO3 (2.5 kb) exhibit distinct patterns of steady-state mRNA expression among multiple human tissues."xsd:string |
| http://purl.uniprot.org/citations/7755634 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1995.1696"xsd:string |
| http://purl.uniprot.org/citations/7755634 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1995.1696"xsd:string |
| http://purl.uniprot.org/citations/7755634 | http://purl.uniprot.org/core/author | "Raben N."xsd:string |
| http://purl.uniprot.org/citations/7755634 | http://purl.uniprot.org/core/author | "Raben N."xsd:string |
| http://purl.uniprot.org/citations/7755634 | http://purl.uniprot.org/core/author | "Miller F.W."xsd:string |
| http://purl.uniprot.org/citations/7755634 | http://purl.uniprot.org/core/author | "Miller F.W."xsd:string |
| http://purl.uniprot.org/citations/7755634 | http://purl.uniprot.org/core/author | "O'Hanlon T.P."xsd:string |
| http://purl.uniprot.org/citations/7755634 | http://purl.uniprot.org/core/author | "O'Hanlon T.P."xsd:string |
| http://purl.uniprot.org/citations/7755634 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7755634 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7755634 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/7755634 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/7755634 | http://purl.uniprot.org/core/pages | "556-566"xsd:string |
| http://purl.uniprot.org/citations/7755634 | http://purl.uniprot.org/core/pages | "556-566"xsd:string |
| http://purl.uniprot.org/citations/7755634 | http://purl.uniprot.org/core/title | "A novel gene oriented in a head-to-head configuration with the human histidyl-tRNA synthetase (HRS) gene encodes an mRNA that predicts a polypeptide homologous to HRS."xsd:string |
| http://purl.uniprot.org/citations/7755634 | http://purl.uniprot.org/core/title | "A novel gene oriented in a head-to-head configuration with the human histidyl-tRNA synthetase (HRS) gene encodes an mRNA that predicts a polypeptide homologous to HRS."xsd:string |
| http://purl.uniprot.org/citations/7755634 | http://purl.uniprot.org/core/volume | "210"xsd:string |
| http://purl.uniprot.org/citations/7755634 | http://purl.uniprot.org/core/volume | "210"xsd:string |
| http://purl.uniprot.org/citations/7755634 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7755634 |
| http://purl.uniprot.org/citations/7755634 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7755634 |
| http://purl.uniprot.org/citations/7755634 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7755634 |
| http://purl.uniprot.org/citations/7755634 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7755634 |