| http://purl.uniprot.org/citations/7773404 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7773404 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7773404 | http://www.w3.org/2000/01/rdf-schema#comment | "Chemical mutagenesis of the AmpC beta-lactamase-hyperinducible Escherichia coli strain SN0301/pNu305 carrying the cloned ampC and ampR genes from Citrobacter freundii OS60 gave four independent mutants in which beta-lactamase was no longer inducible, or was inducible only to a low level, by beta-lactam antibiotics. The genes ampC, ampR, ampD and ampE, which were essential for beta-lactamase induction, were functional in these mutants. In all four mutants, the sites of mutation were mapped to 9.9 min on the E. coli chromosome. Complementation with wild-type ampG restored inducibility of beta-lactamase to wild-type levels. The nucleotide sequence of all four mutant ampG alleles (ampG1, ampG3, ampG4 and ampG5) was determined. In three of the mutants, a single base exchange led to an amino acid change from glycine to aspartate at different sites in the deduced amino acid sequence. In the fourth mutant (ampG4), with low-level inducibility, the nucleotide sequence was identical to wild-type ampG. Spontaneous back-mutation of the chromosomal ampG1 mutant resulted in restoration of wild-type inducibility and a return to the wild-type ampG sequence. Unspecific induction by components of the growth medium was also dependent on intact ampG function."xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://purl.org/dc/terms/identifier | "doi:10.1099/13500872-141-5-1085"xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://purl.org/dc/terms/identifier | "doi:10.1099/13500872-141-5-1085"xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://purl.uniprot.org/core/author | "Schmidt H."xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://purl.uniprot.org/core/author | "Schmidt H."xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://purl.uniprot.org/core/author | "Barth H."xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://purl.uniprot.org/core/author | "Barth H."xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://purl.uniprot.org/core/author | "Korfmann G."xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://purl.uniprot.org/core/author | "Korfmann G."xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://purl.uniprot.org/core/author | "Martin H.H."xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://purl.uniprot.org/core/author | "Martin H.H."xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7773404 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7773404 | http://purl.uniprot.org/core/name | "Microbiology"xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://purl.uniprot.org/core/name | "Microbiology"xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://purl.uniprot.org/core/pages | "1085-1092"xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://purl.uniprot.org/core/pages | "1085-1092"xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://purl.uniprot.org/core/title | "The signal transducer encoded by ampG is essential for induction of chromosomal AmpC beta-lactamase in Escherichia coli by beta-lactam antibiotics and 'unspecific' inducers."xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://purl.uniprot.org/core/title | "The signal transducer encoded by ampG is essential for induction of chromosomal AmpC beta-lactamase in Escherichia coli by beta-lactam antibiotics and 'unspecific' inducers."xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://purl.uniprot.org/core/volume | "141"xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://purl.uniprot.org/core/volume | "141"xsd:string |
| http://purl.uniprot.org/citations/7773404 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7773404 |
| http://purl.uniprot.org/citations/7773404 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7773404 |