RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/7807547http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7807547http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7807547http://www.w3.org/2000/01/rdf-schema#comment"A 3,345-bp fragment of Dictyostelium discoideum mitochondrial DNA (mtDNA) has been sequenced. This fragment contained the 80-kDa subunit of complex I (NADH:ubiquinone oxidoreductase), encoding a predicted amino acid sequence of 688 residues and a molecular mass of 79,805 daltons which is nuclear encoded in other metazoa. The C-terminus of the D. discoideum complex I gene shared a 10-bp overlap with NADH:ubiquinone oxidoreductase chain 5 (ND5), while 21 bp 5' were three tRNA genes (two isoleucine and a histidine) and a further 25 bp 5' of these genes is the partial sequence (104 residues) of an unidentified open reading frame (ORF104). Both the 80-kDa subunit and the ORF104 were hydrophilic and highly charged, suggesting they are not membrane associated, unlike most mitochondrially encoded proteins in the metazoa. Sequence analysis of the 80-kDa subunit, its adjacent ND5 gene, and ORF104 indicates the universal stop codon TGA, which codes for tryptophan in nearly all nonplant mtDNA, is either unassigned or coding for a stop codon in D. discoideum. The large size of the mitochondrial genome (54 kb), the lack of intergenic sequence, and the apparent use of the universal code suggest D. discoideum mtDNA may encode many primitive genes that are nuclear encoded in higher organisms."xsd:string
http://purl.uniprot.org/citations/7807547http://purl.org/dc/terms/identifier"doi:10.1007/bf00160403"xsd:string
http://purl.uniprot.org/citations/7807547http://purl.org/dc/terms/identifier"doi:10.1007/bf00160403"xsd:string
http://purl.uniprot.org/citations/7807547http://purl.org/dc/terms/identifier"doi:10.1007/BF00160403"xsd:string
http://purl.uniprot.org/citations/7807547http://purl.uniprot.org/core/author"Williams K.L."xsd:string
http://purl.uniprot.org/citations/7807547http://purl.uniprot.org/core/author"Williams K.L."xsd:string
http://purl.uniprot.org/citations/7807547http://purl.uniprot.org/core/author"Williams K."xsd:string
http://purl.uniprot.org/citations/7807547http://purl.uniprot.org/core/author"Cole R.A."xsd:string
http://purl.uniprot.org/citations/7807547http://purl.uniprot.org/core/author"Cole R.A."xsd:string
http://purl.uniprot.org/citations/7807547http://purl.uniprot.org/core/author"Cole R."xsd:string
http://purl.uniprot.org/citations/7807547http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/7807547http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/7807547http://purl.uniprot.org/core/name"J. Mol. Evol."xsd:string
http://purl.uniprot.org/citations/7807547http://purl.uniprot.org/core/name"J. Mol. Evol."xsd:string
http://purl.uniprot.org/citations/7807547http://purl.uniprot.org/core/pages"579-588"xsd:string
http://purl.uniprot.org/citations/7807547http://purl.uniprot.org/core/pages"579-588"xsd:string
http://purl.uniprot.org/citations/7807547http://purl.uniprot.org/core/title"The Dictyostelium discoideum mitochondrial genome: a primordial system using the universal code and encoding hydrophilic proteins atypical of metazoan mitochondrial DNA."xsd:string
http://purl.uniprot.org/citations/7807547http://purl.uniprot.org/core/title"The Dictyostelium discoideum mitochondrial genome: a primordial system using the universal code and encoding hydrophilic proteins atypical of metazoan mitochondrial DNA."xsd:string
http://purl.uniprot.org/citations/7807547http://purl.uniprot.org/core/volume"39"xsd:string
http://purl.uniprot.org/citations/7807547http://purl.uniprot.org/core/volume"39"xsd:string
http://purl.uniprot.org/citations/7807547http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/7807547
http://purl.uniprot.org/citations/7807547http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/7807547
http://purl.uniprot.org/citations/7807547http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/7807547