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http://purl.uniprot.org/citations/7846532http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7846532http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7846532http://www.w3.org/2000/01/rdf-schema#comment"Infection of cattle with the protozoan parasite Theileria parva results in a fatal lymphoproliferative syndrome that is associated with the overexpression of casein kinase II. The role of this enzyme in the pathogenesis of lymphoproliferative disorders was investigated by expressing the catalytic subunit in lymphocytes of transgenic mice. Adult transgenic mice displayed a stochastic propensity to develop lymphoma; co-expression of a c-myc transgene in addition to casein kinase II resulted in neonatal leukemia. Thus, the casein kinase II gene can serve as an oncogene, and its dysregulated expression is capable of transforming lymphocytes in a two-step pathway with c-myc."xsd:string
http://purl.uniprot.org/citations/7846532http://purl.org/dc/terms/identifier"doi:10.1126/science.7846532"xsd:string
http://purl.uniprot.org/citations/7846532http://purl.org/dc/terms/identifier"doi:10.1126/science.7846532"xsd:string
http://purl.uniprot.org/citations/7846532http://purl.uniprot.org/core/author"Leder P."xsd:string
http://purl.uniprot.org/citations/7846532http://purl.uniprot.org/core/author"Leder P."xsd:string
http://purl.uniprot.org/citations/7846532http://purl.uniprot.org/core/author"Seldin D.C."xsd:string
http://purl.uniprot.org/citations/7846532http://purl.uniprot.org/core/author"Seldin D.C."xsd:string
http://purl.uniprot.org/citations/7846532http://purl.uniprot.org/core/date"1995"xsd:gYear
http://purl.uniprot.org/citations/7846532http://purl.uniprot.org/core/date"1995"xsd:gYear
http://purl.uniprot.org/citations/7846532http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/7846532http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/7846532http://purl.uniprot.org/core/pages"894-897"xsd:string
http://purl.uniprot.org/citations/7846532http://purl.uniprot.org/core/pages"894-897"xsd:string
http://purl.uniprot.org/citations/7846532http://purl.uniprot.org/core/title"Casein kinase II alpha transgene-induced murine lymphoma: relation to theileriosis in cattle."xsd:string
http://purl.uniprot.org/citations/7846532http://purl.uniprot.org/core/title"Casein kinase II alpha transgene-induced murine lymphoma: relation to theileriosis in cattle."xsd:string
http://purl.uniprot.org/citations/7846532http://purl.uniprot.org/core/volume"267"xsd:string
http://purl.uniprot.org/citations/7846532http://purl.uniprot.org/core/volume"267"xsd:string
http://purl.uniprot.org/citations/7846532http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/7846532
http://purl.uniprot.org/citations/7846532http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/7846532
http://purl.uniprot.org/citations/7846532http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/7846532
http://purl.uniprot.org/citations/7846532http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/7846532
http://purl.uniprot.org/uniprot/Q60737http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/7846532
http://purl.uniprot.org/embl-cds/AAA64563.1http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/7846532