| http://purl.uniprot.org/citations/7848872 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7848872 | http://www.w3.org/2000/01/rdf-schema#comment | "A common feature of the murine Abdominal B (AbdB) -related Hox genes, located in the 5' regions of the four Hox clusters, appears to be a function in patterning the developing limb. As a prerequisite for studying the role of the AbdB-related Hoxc genes during limb development, we have isolated and mapped the three predicted AbdB-related Hoxc-11, -12, and -13 loci, thus defining the 5' end of the Hoxc cluster. Sequence comparisons based on the homeobox sequences of presumably all murine AbdB-related Hox genes strongly support the concept of a two step process in their evolution. As expected, Hoxc-11, -12 and -13 exhibit nested and extremely posteriorly restricted expression domains, whose anterior boundaries reflect their map positions, in accordance with the colinearity rule. A limited comparison of the primary expression domains of all five AbdB-related Hoxc genes in the developing hindlimb revealed nested and increasingly restricted domains of expression in the mesenchyme for only Hoxc-9, -10 and -11. However, separate localized expression was detected for Hoxc-9, -10, -11, -12 and possibly -13 in distal epidermal regions of the developing hind- and forelimb, whereas no expression of any of the five genes was observed in mesenchymal tissues of the developing forelimb. These data suggest a specific role for the AbdB-related Hoxc genes in patterning the hindlimb and pelvic girdle, which is separate from a second role relevant for both hind- and forelimb development."xsd:string |
| http://purl.uniprot.org/citations/7848872 | http://purl.org/dc/terms/identifier | "doi:10.1016/0925-4773(94)90043-4"xsd:string |
| http://purl.uniprot.org/citations/7848872 | http://purl.uniprot.org/core/author | "Peterson R.L."xsd:string |
| http://purl.uniprot.org/citations/7848872 | http://purl.uniprot.org/core/author | "Awgulewitsch A."xsd:string |
| http://purl.uniprot.org/citations/7848872 | http://purl.uniprot.org/core/author | "Papenbrock T."xsd:string |
| http://purl.uniprot.org/citations/7848872 | http://purl.uniprot.org/core/author | "Davda M.M."xsd:string |
| http://purl.uniprot.org/citations/7848872 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/7848872 | http://purl.uniprot.org/core/name | "Mech Dev"xsd:string |
| http://purl.uniprot.org/citations/7848872 | http://purl.uniprot.org/core/pages | "253-260"xsd:string |
| http://purl.uniprot.org/citations/7848872 | http://purl.uniprot.org/core/title | "The murine Hoxc cluster contains five neighboring AbdB-related Hox genes that show unique spatially coordinated expression in posterior embryonic subregions."xsd:string |
| http://purl.uniprot.org/citations/7848872 | http://purl.uniprot.org/core/volume | "47"xsd:string |
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