| http://purl.uniprot.org/citations/7852357 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7852357 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7852357 | http://www.w3.org/2000/01/rdf-schema#comment | "Inositol 1,4,5-trisphosphate receptors (IP3R) are intracellular calcium release channels involved in diverse signaling pathways. An IP3R is thought to play a role in mobilizing calcium required for activation of T lymphocytes. The IP3R is a tetrameric structure comprised of four approximately 300-kDa subunits encoded by a approximately 10-kilobase mRNA. In the present study we determined the structure of the human type 1 IP3R expressed in T lymphocytes (Jurkats). The IP3R in human T cells had a predicted molecular mass of 308 kDa and was most similar to the non-neuronal form of the rodent type 1 IP3R. Two putative tyrosine phosphorylation sites were identified, one near the amino terminus and one near the putative channel pore at the carboxyl terminus. During T cell activation the IP3R was tyrosine phosphorylated. A site-specific anti-IP3R antibody was used to localize the carboxyl terminus of the IP3R to the cytoplasm in T cells."xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.270.6.2833"xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.270.6.2833"xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/author | "Ma Y."xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/author | "Ma Y."xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/author | "Marks A.R."xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/author | "Marks A.R."xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/author | "Go L.O."xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/author | "Go L.O."xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/author | "Jayaraman T."xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/author | "Jayaraman T."xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/author | "Harnick D.J."xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/author | "Harnick D.J."xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/author | "Mulieri P."xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/author | "Mulieri P."xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/date | "1995"xsd:gYear |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/pages | "2833-2840"xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/pages | "2833-2840"xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/title | "The human type 1 inositol 1,4,5-trisphosphate receptor from T lymphocytes. Structure, localization, and tyrosine phosphorylation."xsd:string |
| http://purl.uniprot.org/citations/7852357 | http://purl.uniprot.org/core/title | "The human type 1 inositol 1,4,5-trisphosphate receptor from T lymphocytes. Structure, localization, and tyrosine phosphorylation."xsd:string |