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http://purl.uniprot.org/citations/7857306http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7857306http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7857306http://www.w3.org/2000/01/rdf-schema#comment"Deoxyribonuclease I (DNase I) has recently been implicated in cell death by apoptosis, a process which is frequently accompanied by chromatin DNA degradation. Despite extensive studies on DNase I, its genomic organisation remained unknown. Here we report for the first time on the intron-exon structure of the DNase I gene. The coding region of mouse DNase I is composed of eight introns and eight exons, spanning 2315 base pairs. The deduced protein sequence is 91.5% identical to its rat counterpart, but does not carry the two mutations (Glu13 to D and V67 to I) responsible for the decrease in actin-binding of rat DNase I. The enzymatic activity of mouse DNase I is found in striated muscle, kidney, intestine, liver, lymphnodes, but not in the heart, spleen or pancreas."xsd:string
http://purl.uniprot.org/citations/7857306http://purl.org/dc/terms/identifier"doi:10.1006/bbrc.1995.1153"xsd:string
http://purl.uniprot.org/citations/7857306http://purl.org/dc/terms/identifier"doi:10.1006/bbrc.1995.1153"xsd:string
http://purl.uniprot.org/citations/7857306http://purl.uniprot.org/core/author"Tschopp J."xsd:string
http://purl.uniprot.org/citations/7857306http://purl.uniprot.org/core/author"Tschopp J."xsd:string
http://purl.uniprot.org/citations/7857306http://purl.uniprot.org/core/author"Peitsch M.C."xsd:string
http://purl.uniprot.org/citations/7857306http://purl.uniprot.org/core/author"Peitsch M.C."xsd:string
http://purl.uniprot.org/citations/7857306http://purl.uniprot.org/core/author"French L.E."xsd:string
http://purl.uniprot.org/citations/7857306http://purl.uniprot.org/core/author"French L.E."xsd:string
http://purl.uniprot.org/citations/7857306http://purl.uniprot.org/core/author"Irmler M."xsd:string
http://purl.uniprot.org/citations/7857306http://purl.uniprot.org/core/author"Irmler M."xsd:string
http://purl.uniprot.org/citations/7857306http://purl.uniprot.org/core/date"1995"xsd:gYear
http://purl.uniprot.org/citations/7857306http://purl.uniprot.org/core/date"1995"xsd:gYear
http://purl.uniprot.org/citations/7857306http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/7857306http://purl.uniprot.org/core/name"Biochem. Biophys. Res. Commun."xsd:string
http://purl.uniprot.org/citations/7857306http://purl.uniprot.org/core/pages"62-68"xsd:string
http://purl.uniprot.org/citations/7857306http://purl.uniprot.org/core/pages"62-68"xsd:string
http://purl.uniprot.org/citations/7857306http://purl.uniprot.org/core/title"Genomic organisation and expression of mouse deoxyribonuclease I."xsd:string
http://purl.uniprot.org/citations/7857306http://purl.uniprot.org/core/title"Genomic organisation and expression of mouse deoxyribonuclease I."xsd:string
http://purl.uniprot.org/citations/7857306http://purl.uniprot.org/core/volume"207"xsd:string
http://purl.uniprot.org/citations/7857306http://purl.uniprot.org/core/volume"207"xsd:string
http://purl.uniprot.org/citations/7857306http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/7857306
http://purl.uniprot.org/citations/7857306http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/7857306