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http://purl.uniprot.org/citations/7889410http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7889410http://www.w3.org/2000/01/rdf-schema#comment"Susceptibility to glomerulonephritis (GN) and anti-dsDNA autoantibody production was analyzed in crosses with a newly developed systemic lupus erythematosus-susceptible inbred strain, NZM/Aeg2410. The mode of inheritance and the number and location of systemic lupus erythematosus-associated susceptibility loci were analyzed by interval mapping in a backcross with C57BL/6. Three chromosomal intervals containing strong recessive GN susceptibility alleles were identified on chromosomes 1, 4, and 7, each containing several potentially interesting candidate genes. Heterozygosity at H-2 was also found to correlate strongly with GN susceptibility, consistent with previous findings in the NZB/NZW parental strain model. Logistic regression analysis indicated that each of these susceptibility alleles independently accounted for a component of GN susceptibility, and that susceptibility was inherited as a threshold genetic liability in this model system."xsd:string
http://purl.uniprot.org/citations/7889410http://purl.org/dc/terms/identifier"doi:10.1016/1074-7613(94)90100-7"xsd:string
http://purl.uniprot.org/citations/7889410http://purl.uniprot.org/core/author"Rudofsky U.H."xsd:string
http://purl.uniprot.org/citations/7889410http://purl.uniprot.org/core/author"Wakeland E.K."xsd:string
http://purl.uniprot.org/citations/7889410http://purl.uniprot.org/core/author"Schiffenbauer J."xsd:string
http://purl.uniprot.org/citations/7889410http://purl.uniprot.org/core/author"Morel L."xsd:string
http://purl.uniprot.org/citations/7889410http://purl.uniprot.org/core/author"Longmate J.A."xsd:string
http://purl.uniprot.org/citations/7889410http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/7889410http://purl.uniprot.org/core/name"Immunity"xsd:string
http://purl.uniprot.org/citations/7889410http://purl.uniprot.org/core/pages"219-229"xsd:string
http://purl.uniprot.org/citations/7889410http://purl.uniprot.org/core/title"Polygenic control of susceptibility to murine systemic lupus erythematosus."xsd:string
http://purl.uniprot.org/citations/7889410http://purl.uniprot.org/core/volume"1"xsd:string
http://purl.uniprot.org/citations/7889410http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/7889410
http://purl.uniprot.org/citations/7889410http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/7889410
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http://purl.uniprot.org/uniprot/#_D3Z251-mappedCitation-7889410http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/7889410
http://purl.uniprot.org/uniprot/#_A0A0D6A9T8-mappedCitation-7889410http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/7889410
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http://purl.uniprot.org/uniprot/#_Q62052-mappedCitation-7889410http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/7889410
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http://purl.uniprot.org/uniprot/D6RIQ8http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/7889410
http://purl.uniprot.org/uniprot/Q62052http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/7889410
http://purl.uniprot.org/uniprot/D3Z251http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/7889410