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http://purl.uniprot.org/citations/7889410 | http://www.w3.org/2000/01/rdf-schema#comment | "Susceptibility to glomerulonephritis (GN) and anti-dsDNA autoantibody production was analyzed in crosses with a newly developed systemic lupus erythematosus-susceptible inbred strain, NZM/Aeg2410. The mode of inheritance and the number and location of systemic lupus erythematosus-associated susceptibility loci were analyzed by interval mapping in a backcross with C57BL/6. Three chromosomal intervals containing strong recessive GN susceptibility alleles were identified on chromosomes 1, 4, and 7, each containing several potentially interesting candidate genes. Heterozygosity at H-2 was also found to correlate strongly with GN susceptibility, consistent with previous findings in the NZB/NZW parental strain model. Logistic regression analysis indicated that each of these susceptibility alleles independently accounted for a component of GN susceptibility, and that susceptibility was inherited as a threshold genetic liability in this model system."xsd:string |
http://purl.uniprot.org/citations/7889410 | http://purl.org/dc/terms/identifier | "doi:10.1016/1074-7613(94)90100-7"xsd:string |
http://purl.uniprot.org/citations/7889410 | http://purl.uniprot.org/core/author | "Rudofsky U.H."xsd:string |
http://purl.uniprot.org/citations/7889410 | http://purl.uniprot.org/core/author | "Wakeland E.K."xsd:string |
http://purl.uniprot.org/citations/7889410 | http://purl.uniprot.org/core/author | "Schiffenbauer J."xsd:string |
http://purl.uniprot.org/citations/7889410 | http://purl.uniprot.org/core/author | "Morel L."xsd:string |
http://purl.uniprot.org/citations/7889410 | http://purl.uniprot.org/core/author | "Longmate J.A."xsd:string |
http://purl.uniprot.org/citations/7889410 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/7889410 | http://purl.uniprot.org/core/name | "Immunity"xsd:string |
http://purl.uniprot.org/citations/7889410 | http://purl.uniprot.org/core/pages | "219-229"xsd:string |
http://purl.uniprot.org/citations/7889410 | http://purl.uniprot.org/core/title | "Polygenic control of susceptibility to murine systemic lupus erythematosus."xsd:string |
http://purl.uniprot.org/citations/7889410 | http://purl.uniprot.org/core/volume | "1"xsd:string |
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