| http://purl.uniprot.org/citations/7898759 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7898759 | http://www.w3.org/2000/01/rdf-schema#comment | "Marked changes in the expression of the tachykinin peptide neurokinin B (NKB) have been recently observed in animal models of epilepsy. In this study we investigated mRNA levels encoding the receptor for NKB, the neurokinin-3 receptor (NK-3R), after limbic seizures induced by kainic acid (KA) in the rat. NK-3R mRNA levels were determined by nuclease protection assay at various time intervals after i.p. injection of KA in the rat. Increases of more than 200% were observed in NK-3R mRNA in the cerebellum after 7 and 30 days. In the hippocampus a moderate, reversible increase (of 70%, 1 day after KA) was seen. In the frontal cortex a reduction of NK-3R mRNA (2 days after KA) was found. In the amygdala, levels of the transcript were decreased (by 50% and more) at all intervals investigated. The decreases in mRNA levels in the amygdala are consistent with the severe damage observed in this brain area. The increases in NK-3R mRNA in the cerebellum point to the development of receptor supersensitivity and suggest a functional role of NKB in this animal model of epilepsy."xsd:string |
| http://purl.uniprot.org/citations/7898759 | http://purl.org/dc/terms/identifier | "doi:10.1016/0304-3940(94)90583-5"xsd:string |
| http://purl.uniprot.org/citations/7898759 | http://purl.uniprot.org/core/author | "Roder C."xsd:string |
| http://purl.uniprot.org/citations/7898759 | http://purl.uniprot.org/core/author | "Sperk G."xsd:string |
| http://purl.uniprot.org/citations/7898759 | http://purl.uniprot.org/core/author | "Krause J.E."xsd:string |
| http://purl.uniprot.org/citations/7898759 | http://purl.uniprot.org/core/author | "Bellmann R."xsd:string |
| http://purl.uniprot.org/citations/7898759 | http://purl.uniprot.org/core/author | "McCarson K.E."xsd:string |
| http://purl.uniprot.org/citations/7898759 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/7898759 | http://purl.uniprot.org/core/name | "Neurosci Lett"xsd:string |
| http://purl.uniprot.org/citations/7898759 | http://purl.uniprot.org/core/pages | "158-160"xsd:string |
| http://purl.uniprot.org/citations/7898759 | http://purl.uniprot.org/core/title | "Kainic acid induced seizures cause a marked increase in the expression of neurokinin-3 receptor mRNA in the rat cerebellum."xsd:string |
| http://purl.uniprot.org/citations/7898759 | http://purl.uniprot.org/core/volume | "181"xsd:string |
| http://purl.uniprot.org/citations/7898759 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7898759 |
| http://purl.uniprot.org/citations/7898759 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7898759 |
| http://purl.uniprot.org/uniprot/#_P16177-mappedCitation-7898759 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7898759 |
| http://purl.uniprot.org/uniprot/P16177 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/7898759 |