http://purl.uniprot.org/citations/7902583 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/7902583 | http://www.w3.org/2000/01/rdf-schema#comment | "SWI5 encodes a zinc-finger protein required for expression of the yeast HO gene. Using Swi5 protein that was purified from a bacterial expression system, we previously isolated a yeast factor that stimulates binding of Swi5 to the HO promoter. N-terminal amino acid sequence analysis identified the Swi5 stimulatory factor as the product of the GRF10 gene, which encodes a yeast homeodomain protein. GRF10, also known as PHO2 and BAS2, is a transcriptional activator of the PHO5 acid phosphatase gene and the HIS4 histidine biosynthesis gene. Grf10 protein purified from a bacterial expression system binds DNA cooperatively with Swi5 in vitro. Analysis of disassociation rates indicates that the Grf10-Swi5-DNA complex has a longer half-life than protein-DNA complexes that contain only Swi5 or Grf10. Finally, we show that HO expression is reduced in yeast strains containing grf10 null mutations and that full expression of a heterologous promoter containing a SWI5-dependent HO upstream activation sequence element requires GRF10."xsd:string |
http://purl.uniprot.org/citations/7902583 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.90.23.11237"xsd:string |
http://purl.uniprot.org/citations/7902583 | http://purl.uniprot.org/core/author | "Brazas R.M."xsd:string |
http://purl.uniprot.org/citations/7902583 | http://purl.uniprot.org/core/author | "Stillman D.J."xsd:string |
http://purl.uniprot.org/citations/7902583 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
http://purl.uniprot.org/citations/7902583 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
http://purl.uniprot.org/citations/7902583 | http://purl.uniprot.org/core/pages | "11237-11241"xsd:string |
http://purl.uniprot.org/citations/7902583 | http://purl.uniprot.org/core/title | "The Swi5 zinc-finger and Grf10 homeodomain proteins bind DNA cooperatively at the yeast HO promoter."xsd:string |
http://purl.uniprot.org/citations/7902583 | http://purl.uniprot.org/core/volume | "90"xsd:string |
http://purl.uniprot.org/citations/7902583 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7902583 |
http://purl.uniprot.org/citations/7902583 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7902583 |
http://purl.uniprot.org/uniprot/P07269#attribution-D09A07C7514F8ACCAA76985726394DEC | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/7902583 |
http://purl.uniprot.org/uniprot/P07269#attribution-E9300BCEA41417D4EAD81F147530FA45 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/7902583 |
http://purl.uniprot.org/uniprot/#_P08153-mappedCitation-7902583 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7902583 |
http://purl.uniprot.org/uniprot/#_P07269-mappedCitation-7902583 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7902583 |
http://purl.uniprot.org/uniprot/P07269 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/7902583 |
http://purl.uniprot.org/uniprot/P08153 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/7902583 |