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| http://purl.uniprot.org/citations/7916164 | http://www.w3.org/2000/01/rdf-schema#comment | "After activation in mesoderm and neuroectoderm, expression of the Hoxb-1 gene is progressively restricted to rhombomere (r) 4 in the hindbrain. Analysis of the chick and mouse Hoxb-1 genes identified positive and negative regulatory regions that cooperate to mediate segment-restricted expression during rhombomere formation. An enhancer generates expression extending into r3 and r5, and a repressor limits this domain to r4. The repressor contains a conserved retinoic acid response element, point mutations in which allow expression to spread into adjacent rhombomeres. Retinoids and their nuclear receptors may therefore participate in sharpening segment-restricted expression of Hoxb-1 during rhombomere boundary formation."xsd:string |
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| http://purl.uniprot.org/citations/7916164 | http://purl.uniprot.org/core/author | "Kuroiwa A."xsd:string |
| http://purl.uniprot.org/citations/7916164 | http://purl.uniprot.org/core/author | "Krumlauf R."xsd:string |
| http://purl.uniprot.org/citations/7916164 | http://purl.uniprot.org/core/author | "Marshall H."xsd:string |
| http://purl.uniprot.org/citations/7916164 | http://purl.uniprot.org/core/author | "Studer M."xsd:string |
| http://purl.uniprot.org/citations/7916164 | http://purl.uniprot.org/core/author | "Popperl H."xsd:string |
| http://purl.uniprot.org/citations/7916164 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/7916164 | http://purl.uniprot.org/core/name | "Science"xsd:string |
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| http://purl.uniprot.org/citations/7916164 | http://purl.uniprot.org/core/title | "Role of a conserved retinoic acid response element in rhombomere restriction of Hoxb-1."xsd:string |
| http://purl.uniprot.org/citations/7916164 | http://purl.uniprot.org/core/volume | "265"xsd:string |
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