http://purl.uniprot.org/citations/7920628 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/7920628 | http://www.w3.org/2000/01/rdf-schema#comment | "The beta-subunit of the high-affinity IgE receptor (Fc epsilon RI-beta) on chromosome 11 is maternally linked to atopy, the state of enhanced IgE responsiveness underlying allergic asthma and rhinitis. We have identified a common variant of Fc epsilon RI-beta, lle181Leu within the 4th transmembrane domain. Leu181 shows significant association with positive IgE responses in a random patient sample. Amongst 60 unrelated nuclear families with allergic asthmatic probands, Leu181 is identified in 10 (17%), is maternally inherited in each, and shows a strong association with atopy. Our data indicate that Fc epsilon RI-beta, subject to maternal modification, may be the atopy-causing locus on chromosome 11q."xsd:string |
http://purl.uniprot.org/citations/7920628 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng0694-125"xsd:string |
http://purl.uniprot.org/citations/7920628 | http://purl.uniprot.org/core/author | "Li A."xsd:string |
http://purl.uniprot.org/citations/7920628 | http://purl.uniprot.org/core/author | "Shirakawa T."xsd:string |
http://purl.uniprot.org/citations/7920628 | http://purl.uniprot.org/core/author | "Hopkin J.M."xsd:string |
http://purl.uniprot.org/citations/7920628 | http://purl.uniprot.org/core/author | "Ra C."xsd:string |
http://purl.uniprot.org/citations/7920628 | http://purl.uniprot.org/core/author | "Cookson W.O."xsd:string |
http://purl.uniprot.org/citations/7920628 | http://purl.uniprot.org/core/author | "Dekker J.W."xsd:string |
http://purl.uniprot.org/citations/7920628 | http://purl.uniprot.org/core/author | "Shaw A.E."xsd:string |
http://purl.uniprot.org/citations/7920628 | http://purl.uniprot.org/core/author | "Dubowitz M."xsd:string |
http://purl.uniprot.org/citations/7920628 | http://purl.uniprot.org/core/author | "Faux J.A."xsd:string |
http://purl.uniprot.org/citations/7920628 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/7920628 | http://purl.uniprot.org/core/name | "Nat Genet"xsd:string |
http://purl.uniprot.org/citations/7920628 | http://purl.uniprot.org/core/pages | "125-129"xsd:string |
http://purl.uniprot.org/citations/7920628 | http://purl.uniprot.org/core/title | "Association between atopy and variants of the beta subunit of the high-affinity immunoglobulin E receptor."xsd:string |
http://purl.uniprot.org/citations/7920628 | http://purl.uniprot.org/core/volume | "7"xsd:string |
http://purl.uniprot.org/citations/7920628 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7920628 |
http://purl.uniprot.org/citations/7920628 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7920628 |
http://purl.uniprot.org/uniprot/Q01362#attribution-D3A363FCFBB30397CA545EBA31A80DCC | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/7920628 |