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http://purl.uniprot.org/citations/7929201http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7929201http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7929201http://www.w3.org/2000/01/rdf-schema#comment"Calpain, a calcium-dependent intracellular protease, was identified in Drosophila melanogaster. Drosophila calpain has an amino acid sequence highly homologous to those of mammalian calpains and exhibits a distinct domain structure consisting of cysteine protease and calcium-binding domains. Specific antibodies raised against a recombinant calpain fragment were used to identify the localization of calpain in developing Drosophila embryos. Calpain was first detected near the anterior pole and in posterior region of the embryo just after fertilization. The anterior calpain disappeared during the cleavage cycles. On the other hand, the posterior calpain moved to the posterior pole when polar buds were formed, and condensed just below the pole cells. At cleavage cycles 8 and 9, when nuclei reached the egg surface, calpain was localized between the nuclei at the surface beneath the precleavage furrows. Co-staining experiments with anti-actin antibody revealed that calpain condenses specifically at the edge of and between actin caps that underlie the plasma membrane immediately above each nucleus. These results indicate that calpain is involved in the dynamic changes in the embryonic cytoskeleton, especially actin-related structures, during early embryogenesis prior to cellularization."xsd:string
http://purl.uniprot.org/citations/7929201http://purl.org/dc/terms/identifier"doi:10.1016/s0021-9258(17)31508-9"xsd:string
http://purl.uniprot.org/citations/7929201http://purl.org/dc/terms/identifier"doi:10.1016/s0021-9258(17)31508-9"xsd:string
http://purl.uniprot.org/citations/7929201http://purl.uniprot.org/core/author"Emori Y."xsd:string
http://purl.uniprot.org/citations/7929201http://purl.uniprot.org/core/author"Emori Y."xsd:string
http://purl.uniprot.org/citations/7929201http://purl.uniprot.org/core/author"Saigo K."xsd:string
http://purl.uniprot.org/citations/7929201http://purl.uniprot.org/core/author"Saigo K."xsd:string
http://purl.uniprot.org/citations/7929201http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/7929201http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/7929201http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/7929201http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/7929201http://purl.uniprot.org/core/pages"25137-25142"xsd:string
http://purl.uniprot.org/citations/7929201http://purl.uniprot.org/core/pages"25137-25142"xsd:string
http://purl.uniprot.org/citations/7929201http://purl.uniprot.org/core/title"Calpain localization changes in coordination with actin-related cytoskeletal changes during early embryonic development of Drosophila."xsd:string
http://purl.uniprot.org/citations/7929201http://purl.uniprot.org/core/title"Calpain localization changes in coordination with actin-related cytoskeletal changes during early embryonic development of Drosophila."xsd:string
http://purl.uniprot.org/citations/7929201http://purl.uniprot.org/core/volume"269"xsd:string
http://purl.uniprot.org/citations/7929201http://purl.uniprot.org/core/volume"269"xsd:string
http://purl.uniprot.org/citations/7929201http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/7929201
http://purl.uniprot.org/citations/7929201http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/7929201
http://purl.uniprot.org/citations/7929201http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/7929201
http://purl.uniprot.org/citations/7929201http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/7929201
http://purl.uniprot.org/uniprot/Q11002http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/7929201
http://purl.uniprot.org/embl-cds/CAA55298.1http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/7929201