| http://purl.uniprot.org/citations/7939685 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7939685 | http://www.w3.org/2000/01/rdf-schema#comment | "Mice lacking the proto-oncogene c-fos develop the bone disease osteopetrosis. Fos mutant mice were found to have a block in the differentiation of bone-resorbing osteoclasts that was intrinsic to hematopoietic cells. Bone marrow transplantation rescued the osteopetrosis, and ectopic c-fos expression overcame this differentiation block. The lack of Fos also caused a lineage shift between osteoclasts and macrophages that resulted in increased numbers of bone marrow macrophages. These results identify Fos as a key regulator of osteoclast-macrophage lineage determination in vivo and provide insights into the molecular mechanisms underlying metabolic bone diseases."xsd:string |
| http://purl.uniprot.org/citations/7939685 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.7939685"xsd:string |
| http://purl.uniprot.org/citations/7939685 | http://purl.uniprot.org/core/author | "Wagner E.F."xsd:string |
| http://purl.uniprot.org/citations/7939685 | http://purl.uniprot.org/core/author | "Felix R."xsd:string |
| http://purl.uniprot.org/citations/7939685 | http://purl.uniprot.org/core/author | "Wang Z.Q."xsd:string |
| http://purl.uniprot.org/citations/7939685 | http://purl.uniprot.org/core/author | "Cecchini M.G."xsd:string |
| http://purl.uniprot.org/citations/7939685 | http://purl.uniprot.org/core/author | "Hofstetter W."xsd:string |
| http://purl.uniprot.org/citations/7939685 | http://purl.uniprot.org/core/author | "Grigoriadis A.E."xsd:string |
| http://purl.uniprot.org/citations/7939685 | http://purl.uniprot.org/core/author | "Fleisch H.A."xsd:string |
| http://purl.uniprot.org/citations/7939685 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/7939685 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/7939685 | http://purl.uniprot.org/core/pages | "443-448"xsd:string |
| http://purl.uniprot.org/citations/7939685 | http://purl.uniprot.org/core/title | "c-Fos: a key regulator of osteoclast-macrophage lineage determination and bone remodeling."xsd:string |
| http://purl.uniprot.org/citations/7939685 | http://purl.uniprot.org/core/volume | "266"xsd:string |
| http://purl.uniprot.org/citations/7939685 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7939685 |
| http://purl.uniprot.org/citations/7939685 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7939685 |
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| http://purl.uniprot.org/uniprot/#_Q3U463-mappedCitation-7939685 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/7939685 |
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