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http://purl.uniprot.org/citations/7959009http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7959009http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7959009http://www.w3.org/2000/01/rdf-schema#comment"A+U-rich elements (ARE) serve to control the degradation of some proto-oncogene and lymphokine mRNAs. The protein, AUF1, which consists of two polypeptides of 37 and 40 kDa (p37 and p40, respectively) when purified from cytosol, has been implicated in ARE-directed mRNA turnover due to its binding to ARE. Molecular cloning of a cDNA (p37AUF1) corresponding to human p37 predicted a polypeptide containing two non-identical RNA recognition motifs (RRM) and a C-terminal Gln-rich domain [Zhang et al. Mol. Cell. Biol. 13 (1993) 7652-7665]. Two cDNAs, designated muAUF1-3 and muAUF1-7, were isolated from a murine fetal cDNA library, using as a probe, a fragment of the p37AUF1 cDNA encoding RRM1 and approximately half of RRM2. The muAUF1-3 open reading frame (ORF) was very homologous to human p37AUF1 with the greatest homology between the corresponding RRMs and the C-terminal Gln-rich motif. Clone muAUF1-7 was highly homologous to muAUF1-3, but was truncated within the region encoding the RNP-1 box in RRM2. Clone muAUF1-3 encoded 19 amino acids in RRM1 not encoded by either muAUF1-7 or human p37AUF1. Such alterations in sequence could modify the RNA-binding properties of these proteins and have concomitant effects on ARE-directed posttranscriptional processes."xsd:string
http://purl.uniprot.org/citations/7959009http://purl.uniprot.org/core/name"Gene"xsd:string
http://purl.uniprot.org/citations/7959009http://purl.uniprot.org/core/name"Gene"xsd:string
http://purl.uniprot.org/citations/7959009http://purl.org/dc/terms/identifier"doi:10.1016/0378-1119(94)90168-6"xsd:string
http://purl.uniprot.org/citations/7959009http://purl.org/dc/terms/identifier"doi:10.1016/0378-1119(94)90168-6"xsd:string
http://purl.uniprot.org/citations/7959009http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/7959009
http://purl.uniprot.org/citations/7959009http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/7959009
http://purl.uniprot.org/citations/7959009http://purl.uniprot.org/core/author"Long L."xsd:string
http://purl.uniprot.org/citations/7959009http://purl.uniprot.org/core/author"Long L."xsd:string
http://purl.uniprot.org/citations/7959009http://purl.uniprot.org/core/author"Brewer G."xsd:string
http://purl.uniprot.org/citations/7959009http://purl.uniprot.org/core/author"Brewer G."xsd:string
http://purl.uniprot.org/citations/7959009http://purl.uniprot.org/core/author"Ehrenman K."xsd:string
http://purl.uniprot.org/citations/7959009http://purl.uniprot.org/core/author"Ehrenman K."xsd:string
http://purl.uniprot.org/citations/7959009http://purl.uniprot.org/core/author"Wagner B.J."xsd:string
http://purl.uniprot.org/citations/7959009http://purl.uniprot.org/core/author"Wagner B.J."xsd:string
http://purl.uniprot.org/citations/7959009http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/7959009http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/7959009http://purl.uniprot.org/core/pages"315-319"xsd:string
http://purl.uniprot.org/citations/7959009http://purl.uniprot.org/core/pages"315-319"xsd:string
http://purl.uniprot.org/citations/7959009http://purl.uniprot.org/core/title"Characterization of cDNAs encoding the murine A+U-rich RNA-binding protein AUF1."xsd:string
http://purl.uniprot.org/citations/7959009http://purl.uniprot.org/core/title"Characterization of cDNAs encoding the murine A+U-rich RNA-binding protein AUF1."xsd:string
http://purl.uniprot.org/citations/7959009http://purl.uniprot.org/core/volume"149"xsd:string
http://purl.uniprot.org/citations/7959009http://purl.uniprot.org/core/volume"149"xsd:string