| http://purl.uniprot.org/citations/7961436 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7961436 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7961436 | http://www.w3.org/2000/01/rdf-schema#comment | "The sxy-1 mutation of Haemophilus influenzae causes a 100-to 1,000-fold increase in spontaneous natural competence. We have used mapping and sequencing to identify this mutation as a G-to-A transition in an open reading frame adjacent to the rec-1 locus. This mutation substitutes valine for isoleucine at amino acid 19 of the protein specified by this gene (now named sxy). A multicopy plasmid containing the wild-type sxy gene confers constitutive competence on wild-type cells. Cells carrying this plasmid exhibit, in all stages of growth, DNA uptake levels and transformation frequencies as high those normally seen only after full induction of competence by starvation; deletion of part of the sxy gene from the plasmid abolishes this effect. In contrast, a transposon insertion in sxy entirely prevents both DNA uptake and transformation, indicating that sxy encodes a function essential for competence. These findings suggest that sxy may act as a positive regulator of competence. However, because cells carrying the transposon-inactivated sxy::Tn allele grow slowly under conditions that do not induce competence, sxy may also have a role in noncompetent cells."xsd:string |
| http://purl.uniprot.org/citations/7961436 | http://purl.org/dc/terms/identifier | "doi:10.1128/jb.176.22.6789-6794.1994"xsd:string |
| http://purl.uniprot.org/citations/7961436 | http://purl.org/dc/terms/identifier | "doi:10.1128/jb.176.22.6789-6794.1994"xsd:string |
| http://purl.uniprot.org/citations/7961436 | http://purl.uniprot.org/core/author | "Redfield R.J."xsd:string |
| http://purl.uniprot.org/citations/7961436 | http://purl.uniprot.org/core/author | "Redfield R.J."xsd:string |
| http://purl.uniprot.org/citations/7961436 | http://purl.uniprot.org/core/author | "Williams P.M."xsd:string |
| http://purl.uniprot.org/citations/7961436 | http://purl.uniprot.org/core/author | "Williams P.M."xsd:string |
| http://purl.uniprot.org/citations/7961436 | http://purl.uniprot.org/core/author | "Bannister L.A."xsd:string |
| http://purl.uniprot.org/citations/7961436 | http://purl.uniprot.org/core/author | "Bannister L.A."xsd:string |
| http://purl.uniprot.org/citations/7961436 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/7961436 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/7961436 | http://purl.uniprot.org/core/name | "J. Bacteriol."xsd:string |
| http://purl.uniprot.org/citations/7961436 | http://purl.uniprot.org/core/name | "J. Bacteriol."xsd:string |
| http://purl.uniprot.org/citations/7961436 | http://purl.uniprot.org/core/pages | "6789-6794"xsd:string |
| http://purl.uniprot.org/citations/7961436 | http://purl.uniprot.org/core/pages | "6789-6794"xsd:string |
| http://purl.uniprot.org/citations/7961436 | http://purl.uniprot.org/core/title | "The Haemophilus influenzae sxy-1 mutation is in a newly identified gene essential for competence."xsd:string |
| http://purl.uniprot.org/citations/7961436 | http://purl.uniprot.org/core/title | "The Haemophilus influenzae sxy-1 mutation is in a newly identified gene essential for competence."xsd:string |
| http://purl.uniprot.org/citations/7961436 | http://purl.uniprot.org/core/volume | "176"xsd:string |
| http://purl.uniprot.org/citations/7961436 | http://purl.uniprot.org/core/volume | "176"xsd:string |
| http://purl.uniprot.org/citations/7961436 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7961436 |
| http://purl.uniprot.org/citations/7961436 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7961436 |
| http://purl.uniprot.org/citations/7961436 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7961436 |
| http://purl.uniprot.org/citations/7961436 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/7961436 |