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http://purl.uniprot.org/citations/7969142http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7969142http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/7969142http://www.w3.org/2000/01/rdf-schema#comment"To isolate Saccharomyces cerevisiae mutants defective in recombinational DNA repair, we constructed a strain that contains duplicated ura3 alleles that flank LEU2 and ADE5 genes at the ura3 locus on chromosome V. When a HO endonuclease cleavage site is located within one of the ura3 alleles, Ura+ recombination is increased over 100-fold in wild-type strains following HO induction from the GAL1, 10 promoter. This strain was used to screen for mutants that exhibited reduced levels of HO-induced intrachromosomal recombination without significantly affecting the spontaneous frequency of Ura+ recombination. One of the mutations isolated through this screen was found to affect the essential gene CDC1. This mutation, cdc1-100, completely eliminated HO-induced Ura+ recombination yet maintained both spontaneous preinduced recombination levels and cell viability, cdc1-100 mutants were moderately sensitive to killing by methyl methanesulfonate and gamma irradiation. The effect of the cdc1-100 mutation on recombinational double-strand break repair indicates that a recombinationally silent mechanism other than sister chromatid exchange was responsible for the efficient repair of DNA double-strand breaks."xsd:string
http://purl.uniprot.org/citations/7969142http://purl.org/dc/terms/identifier"doi:10.1128/mcb.14.12.8037-8050.1994"xsd:string
http://purl.uniprot.org/citations/7969142http://purl.org/dc/terms/identifier"doi:10.1128/mcb.14.12.8037-8050.1994"xsd:string
http://purl.uniprot.org/citations/7969142http://purl.uniprot.org/core/author"Halbrook J."xsd:string
http://purl.uniprot.org/citations/7969142http://purl.uniprot.org/core/author"Halbrook J."xsd:string
http://purl.uniprot.org/citations/7969142http://purl.uniprot.org/core/author"Hoekstra M.F."xsd:string
http://purl.uniprot.org/citations/7969142http://purl.uniprot.org/core/author"Hoekstra M.F."xsd:string
http://purl.uniprot.org/citations/7969142http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/7969142http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/7969142http://purl.uniprot.org/core/name"Mol. Cell. Biol."xsd:string
http://purl.uniprot.org/citations/7969142http://purl.uniprot.org/core/name"Mol. Cell. Biol."xsd:string
http://purl.uniprot.org/citations/7969142http://purl.uniprot.org/core/pages"8037-8050"xsd:string
http://purl.uniprot.org/citations/7969142http://purl.uniprot.org/core/pages"8037-8050"xsd:string
http://purl.uniprot.org/citations/7969142http://purl.uniprot.org/core/title"Mutations in the Saccharomyces cerevisiae CDC1 gene affect double-strand-break-induced intrachromosomal recombination."xsd:string
http://purl.uniprot.org/citations/7969142http://purl.uniprot.org/core/title"Mutations in the Saccharomyces cerevisiae CDC1 gene affect double-strand-break-induced intrachromosomal recombination."xsd:string
http://purl.uniprot.org/citations/7969142http://purl.uniprot.org/core/volume"14"xsd:string
http://purl.uniprot.org/citations/7969142http://purl.uniprot.org/core/volume"14"xsd:string
http://purl.uniprot.org/citations/7969142http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/7969142
http://purl.uniprot.org/citations/7969142http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/7969142
http://purl.uniprot.org/citations/7969142http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/7969142
http://purl.uniprot.org/citations/7969142http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/7969142
http://purl.uniprot.org/uniprot/P40986http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/7969142
http://purl.uniprot.org/embl-cds/CAA57411.1http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/7969142