| http://purl.uniprot.org/citations/7997179 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7997179 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/7997179 | http://www.w3.org/2000/01/rdf-schema#comment | "Haemophilus influenzae infections are preceded by airway colonization, a process facilitated by fimbriae. Here, we identified the complete fimbrial gene cluster of H. influenzae type b. HifA forms the major subunit. HifB, a periplasmic chaperone, and HifC, an outer membrane usher, are typical assembly genes; their inactivation abolished fimbriae formation. HifD and HifE are putative minor subunits, both participating in fimbriae biogenesis. Inactivation of either one drastically reduced fimbriae expression. HifD represents a novel type of fimbrial subunit with lipoprotein characteristics, pointing to a membrane-associated function of HifD. Transcription of all fimbrial genes is coregulated through two clustered promoters. The flanking of the fimbrial gene cluster by repetitive extragenic palindromic sequences together with a partial duplication of an adjacent unrelated operon indicated that the cluster was once inserted in the H. influenzae genome as a mobile virulence unit."xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1365-2958.1994.tb00461.x"xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1365-2958.1994.tb00461.x"xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://purl.uniprot.org/core/author | "van Putten J.P.M."xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://purl.uniprot.org/core/author | "van Putten J.P.M."xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://purl.uniprot.org/core/author | "Mooi F.R."xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://purl.uniprot.org/core/author | "Mooi F.R."xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://purl.uniprot.org/core/author | "van Alphen L."xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://purl.uniprot.org/core/author | "van Alphen L."xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://purl.uniprot.org/core/author | "van Ham M.S."xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://purl.uniprot.org/core/author | "van Ham M.S."xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/7997179 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/7997179 | http://purl.uniprot.org/core/name | "Mol. Microbiol."xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://purl.uniprot.org/core/name | "Mol. Microbiol."xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://purl.uniprot.org/core/pages | "673-684"xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://purl.uniprot.org/core/pages | "673-684"xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://purl.uniprot.org/core/title | "The fimbrial gene cluster of Haemophilus influenzae type b."xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://purl.uniprot.org/core/title | "The fimbrial gene cluster of Haemophilus influenzae type b."xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://purl.uniprot.org/core/volume | "13"xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://purl.uniprot.org/core/volume | "13"xsd:string |
| http://purl.uniprot.org/citations/7997179 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7997179 |
| http://purl.uniprot.org/citations/7997179 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/7997179 |