| http://purl.uniprot.org/citations/8001151 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8001151 | http://www.w3.org/2000/01/rdf-schema#comment | "Peroxisome proliferator-activated receptor gamma 2 (PPAR gamma 2) is an adipocyte-specific nuclear hormone receptor that has recently been identified as a key regulator of two fat cell enhancers. Transcriptional activation by PPAR gamma 2 is potentiated by a variety of lipids and lipid-like compounds, including naturally occurring polyunsaturated fatty acids. We demonstrate here that retroviral expression of PPAR gamma 2 stimulates adipose differentiation of cultured fibroblasts. PPAR activators promote the differentiation of PPAR gamma 2-expressing cells in a dose-dependent manner. C/EBP alpha, a second transcription factor induced during adipocyte differentiation, can cooperate with PPAR gamma 2 to stimulate the adipocyte program dramatically. Our results suggest that the physiologic role of PPAR gamma 2 is to regulate development of the adipose lineage in response to endogenous lipid activators and that this factor may serve to link the process of adipocyte differentiation to systemic lipid metabolism."xsd:string |
| http://purl.uniprot.org/citations/8001151 | http://purl.org/dc/terms/identifier | "doi:10.1016/0092-8674(94)90006-x"xsd:string |
| http://purl.uniprot.org/citations/8001151 | http://purl.uniprot.org/core/author | "Spiegelman B.M."xsd:string |
| http://purl.uniprot.org/citations/8001151 | http://purl.uniprot.org/core/author | "Hu E."xsd:string |
| http://purl.uniprot.org/citations/8001151 | http://purl.uniprot.org/core/author | "Tontonoz P."xsd:string |
| http://purl.uniprot.org/citations/8001151 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/8001151 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/8001151 | http://purl.uniprot.org/core/pages | "1147-1156"xsd:string |
| http://purl.uniprot.org/citations/8001151 | http://purl.uniprot.org/core/title | "Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor."xsd:string |
| http://purl.uniprot.org/citations/8001151 | http://purl.uniprot.org/core/volume | "79"xsd:string |
| http://purl.uniprot.org/citations/8001151 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8001151 |
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