| http://purl.uniprot.org/citations/8005442 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8005442 | http://www.w3.org/2000/01/rdf-schema#comment | "In Caenorhabditis elegans, formation of the developmentally arrested dauer larva is induced by high levels of a constitutively secreted pheromone. Synergy between two groups of incompletely penetrant dauer-constitutive (Daf-c) mutations has recently led to a proposal that these two groups of genes are partially redundant and function in two parallel pathways that regulate dauer formation. A possible weakness in this reasoning is that the mutations used to identify the synergy were specifically obtained as incompletely penetrant mutations. Here we use screens to identify new Daf-c alleles without any requirement for partial penetrance. Nevertheless, 22 of the 25 new mutations are incompletely penetrant mutations in 6 previously identified genes. Among these are mutations in daf-8 and daf-19, genes for which only one mutation had been previously identified. Also included in this group are three daf-1 alleles that do not exhibit the maternal rescue characteristic of other daf-1 alleles. Two of the 25 new mutations are fully penetrant and are alleles of daf-2, the one gene in which a fully penetrant mutation had been found earlier. Finally, one of the 25 new mutations is semidominant, temperature-sensitive, and identifies a new gene, daf-28. The results demonstrate that an incompletely penetrant Daf-c phenotype is characteristic of mutations in most Daf-c genes other than daf-2. This finding strengthens the hypothesis that a branched genetic pathway controls dauer formation."xsd:string |
| http://purl.uniprot.org/citations/8005442 | http://purl.org/dc/terms/identifier | "doi:10.1093/genetics/136.3.879"xsd:string |
| http://purl.uniprot.org/citations/8005442 | http://purl.uniprot.org/core/author | "Thomas J.H."xsd:string |
| http://purl.uniprot.org/citations/8005442 | http://purl.uniprot.org/core/author | "Malone E.A."xsd:string |
| http://purl.uniprot.org/citations/8005442 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/8005442 | http://purl.uniprot.org/core/name | "Genetics"xsd:string |
| http://purl.uniprot.org/citations/8005442 | http://purl.uniprot.org/core/pages | "879-886"xsd:string |
| http://purl.uniprot.org/citations/8005442 | http://purl.uniprot.org/core/title | "A screen for nonconditional dauer-constitutive mutations in Caenorhabditis elegans."xsd:string |
| http://purl.uniprot.org/citations/8005442 | http://purl.uniprot.org/core/volume | "136"xsd:string |
| http://purl.uniprot.org/citations/8005442 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8005442 |
| http://purl.uniprot.org/citations/8005442 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8005442 |
| http://purl.uniprot.org/uniprot/#_A0A131MB12-mappedCitation-8005442 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8005442 |
| http://purl.uniprot.org/uniprot/#_A0A131MBJ8-mappedCitation-8005442 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8005442 |
| http://purl.uniprot.org/uniprot/#_A0A0K3AUK6-mappedCitation-8005442 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8005442 |
| http://purl.uniprot.org/uniprot/#_A0A0K3AXA0-mappedCitation-8005442 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8005442 |
| http://purl.uniprot.org/uniprot/#_A0A0K3ARE8-mappedCitation-8005442 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8005442 |
| http://purl.uniprot.org/uniprot/#_A0A0K3ARZ1-mappedCitation-8005442 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8005442 |
| http://purl.uniprot.org/uniprot/#_A0A0K3AUA1-mappedCitation-8005442 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8005442 |
| http://purl.uniprot.org/uniprot/#_G8JY02-mappedCitation-8005442 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8005442 |
| http://purl.uniprot.org/uniprot/#_P50488-mappedCitation-8005442 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8005442 |
| http://purl.uniprot.org/uniprot/#_Q21733-mappedCitation-8005442 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8005442 |
| http://purl.uniprot.org/uniprot/#_Q09555-mappedCitation-8005442 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8005442 |
| http://purl.uniprot.org/uniprot/#_P20792-mappedCitation-8005442 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8005442 |
| http://purl.uniprot.org/uniprot/#_P92172-mappedCitation-8005442 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8005442 |