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http://purl.uniprot.org/citations/8009226http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8009226http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8009226http://www.w3.org/2000/01/rdf-schema#comment"A 175-kilodalton erythrocyte binding protein, EBA-175, of the parasite Plasmodium falciparum mediates the invasion of erythrocytes. The erythrocyte receptor for EBA-175 is dependent on sialic acid. The domain of EBA-175 that binds erythrocytes was identified as region II with the use of truncated portions of EBA-175 expressed on COS cells. Region II, which contains a cysteine-rich motif, and native EBA-175 bind specifically to glycophorin A, but not to glycophorin B, on the erythrocyte membrane. Erythrocyte recognition of EBA-175 requires both sialic acid and the peptide backbone of glycophorin A. The identification of both the receptor and ligand domains may suggest rational designs for receptor blockade and vaccines."xsd:string
http://purl.uniprot.org/citations/8009226http://purl.org/dc/terms/identifier"doi:10.1126/science.8009226"xsd:string
http://purl.uniprot.org/citations/8009226http://purl.org/dc/terms/identifier"doi:10.1126/science.8009226"xsd:string
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/author"Chitnis C.E."xsd:string
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/author"Chitnis C.E."xsd:string
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/author"Miller L.H."xsd:string
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/author"Miller L.H."xsd:string
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/author"Hadley T.J."xsd:string
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/author"Hadley T.J."xsd:string
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/author"Sim B.K."xsd:string
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/author"Sim B.K."xsd:string
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/author"Wasniowska K."xsd:string
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/author"Wasniowska K."xsd:string
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/pages"1941-1944"xsd:string
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/pages"1941-1944"xsd:string
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/title"Receptor and ligand domains for invasion of erythrocytes by Plasmodium falciparum."xsd:string
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/title"Receptor and ligand domains for invasion of erythrocytes by Plasmodium falciparum."xsd:string
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/volume"264"xsd:string
http://purl.uniprot.org/citations/8009226http://purl.uniprot.org/core/volume"264"xsd:string