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http://purl.uniprot.org/citations/8015379http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8015379http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8015379http://www.w3.org/2000/01/rdf-schema#comment"Expression of the alpha-subunit of the taste-specific G protein alpha-gustducin and the glycolytic enzyme neuron-specific enolase (NSE) was investigated immunohistochemically in human circumvallate and foliate taste papillae. Immunofluorescence for alpha-gustducin was observed in taste cells of both types of papillae and exhibited two patterns of immunofluorescence, plasmalemmal and cytosolic. The plasmalemmal pattern showed intense immunofluorescence localized to the apical region, and was exhibited by most immunoreactive taste cells. In contrast, the cytosolic pattern, observed in one or two immunoreactive cells in a taste bud per section, showed immunofluorescence distributed throughout the cytoplasm. A subpopulation of alpha-gustducin-immunoreactive taste receptor cells, most of which exhibited the cytosolic pattern, also expressed NSE. Optical sectioning, using confocal laser scanning microscopy, demonstrated the highest level of expression of alpha-gustducin in the apical microvillar region of the taste cells in close apposition to the taste pore. These studies indicate conservation of epitopes of alpha-gustducin in humans and rats, and suggest that this G protein is associated with taste transduction in both rats and humans. The patterns of expression of alpha-gustducin, and coexpression with NSE, may correlate with specialized subtypes or developmental stages of taste receptor cells."xsd:string
http://purl.uniprot.org/citations/8015379http://purl.org/dc/terms/identifier"doi:10.1016/0169-328x(94)90047-7"xsd:string
http://purl.uniprot.org/citations/8015379http://purl.org/dc/terms/identifier"doi:10.1016/0169-328x(94)90047-7"xsd:string
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/author"Takami S."xsd:string
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/author"Takami S."xsd:string
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/author"McLaughlin S.K."xsd:string
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/author"McLaughlin S.K."xsd:string
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/author"Margolskee R.F."xsd:string
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/author"Margolskee R.F."xsd:string
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/author"Getchell M.L."xsd:string
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/author"Getchell M.L."xsd:string
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/author"Getchell T.V."xsd:string
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/author"Getchell T.V."xsd:string
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/name"Brain Res. Mol. Brain Res."xsd:string
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/name"Brain Res. Mol. Brain Res."xsd:string
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/pages"193-203"xsd:string
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/pages"193-203"xsd:string
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/title"Human taste cells express the G protein alpha-gustducin and neuron-specific enolase."xsd:string
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/title"Human taste cells express the G protein alpha-gustducin and neuron-specific enolase."xsd:string
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/volume"22"xsd:string
http://purl.uniprot.org/citations/8015379http://purl.uniprot.org/core/volume"22"xsd:string