| http://purl.uniprot.org/citations/8021272 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8021272 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8021272 | http://www.w3.org/2000/01/rdf-schema#comment | "The kappa B enhancer element regulates expression of many genes involved in immune responses and other processes. kappa B motif binds a number of proteins, some but not all, are related to the NF-kappa B family of transcription factors. We have previously identified a 65-kDa phosphoprotein that is specifically recognized by the kappa B motif (Ostrowski, J., Sims, J. E., Sibley, C. H., Valentine, M. A., Dower, S. K., Meier, K. E., and Bomsztyk, K. (1991) J. Biol. Chem. 266, 12722-12733). This protein is closely associated with a serine/threonine kinase that is responsive to treatment of cells with interleukin-1 and other agents. We report here purification, cloning, and expression of this kappa B motif-binding phosphoprotein. The primary structure deduced from the isolated murine cDNA, identifies the protein as the homolog of the human heterogeneous nuclear ribonucleoprotein K protein. Antipeptide antibodies and expression of the cloned cDNA in Escherichia coli, demonstrated that the K protein is the authentic phosphoprotein that binds the kappa B motif in vitro. We also demonstrate that the in vitro phosphorylation of the natural and the recombinant K proteins by the associated kinase is stimulated by the kappa B motif."xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(17)32487-0"xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(17)32487-0"xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/author | "Ostrowski J."xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/author | "Ostrowski J."xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/author | "Rauch C.T."xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/author | "Rauch C.T."xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/author | "McMullen B.A."xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/author | "McMullen B.A."xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/author | "Sleath P.R."xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/author | "Sleath P.R."xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/author | "Bomsztyk K."xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/author | "Bomsztyk K."xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/author | "Seger R."xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/author | "Seger R."xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/author | "van Seuningen I."xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/author | "van Seuningen I."xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/pages | "17626-17634"xsd:string |
| http://purl.uniprot.org/citations/8021272 | http://purl.uniprot.org/core/pages | "17626-17634"xsd:string |