http://purl.uniprot.org/citations/8022816 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8022816 | http://www.w3.org/2000/01/rdf-schema#comment | "Mice with a homozygous deletion in their Tap-1 gene (-/-mice) express very low levels of cell membrane major histocompatibility complex class I molecules and have < 1% peripheral CD8+ T cells. We show that these -/-mice but not their +/-littermates display strong primary syngeneic anti-H-2Kb and -Db-specific responses mediated by CD8+ T cells. These responses are augmented by in vivo priming. Further, -/-mice primed in vivo with H-2d alloantigens generate an anti-H-2d response which appears nearly as strong as that found in +/- littermates. Both -/-anti-H-2b and anti-H-2d T cells do not recognize target cells from Tap-1 -/-animals or Tap-2-deficient RMA-S cells. Thus, some CD8+ anti-self and alloreactive T cells can be selected in the absence of Tap proteins."xsd:string |
http://purl.uniprot.org/citations/8022816 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.91.14.6525"xsd:string |
http://purl.uniprot.org/citations/8022816 | http://purl.uniprot.org/core/author | "Ljunggren H.G."xsd:string |
http://purl.uniprot.org/citations/8022816 | http://purl.uniprot.org/core/author | "Tonegawa S."xsd:string |
http://purl.uniprot.org/citations/8022816 | http://purl.uniprot.org/core/author | "Ashton-Rickardt P.G."xsd:string |
http://purl.uniprot.org/citations/8022816 | http://purl.uniprot.org/core/author | "Forman J."xsd:string |
http://purl.uniprot.org/citations/8022816 | http://purl.uniprot.org/core/author | "Van Kaer L."xsd:string |
http://purl.uniprot.org/citations/8022816 | http://purl.uniprot.org/core/author | "Aldrich C.J."xsd:string |
http://purl.uniprot.org/citations/8022816 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/8022816 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
http://purl.uniprot.org/citations/8022816 | http://purl.uniprot.org/core/pages | "6525-6528"xsd:string |
http://purl.uniprot.org/citations/8022816 | http://purl.uniprot.org/core/title | "Positive selection of self- and alloreactive CD8+ T cells in Tap-1 mutant mice."xsd:string |
http://purl.uniprot.org/citations/8022816 | http://purl.uniprot.org/core/volume | "91"xsd:string |
http://purl.uniprot.org/citations/8022816 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8022816 |
http://purl.uniprot.org/citations/8022816 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8022816 |
http://purl.uniprot.org/uniprot/#_A0A068BER1-mappedCitation-8022816 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8022816 |
http://purl.uniprot.org/uniprot/#_F6QHF1-mappedCitation-8022816 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8022816 |
http://purl.uniprot.org/uniprot/#_Q3U543-mappedCitation-8022816 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8022816 |
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http://purl.uniprot.org/uniprot/#_Q64333-mappedCitation-8022816 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8022816 |
http://purl.uniprot.org/uniprot/#_Q3U6V4-mappedCitation-8022816 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8022816 |
http://purl.uniprot.org/uniprot/#_P01887-mappedCitation-8022816 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8022816 |
http://purl.uniprot.org/uniprot/#_P21958-mappedCitation-8022816 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/8022816 |