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http://purl.uniprot.org/citations/8029325http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8029325http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8029325http://www.w3.org/2000/01/rdf-schema#comment"The complete nucleotide sequence of Ddp1, a high copy number 13.7-kbp endogenous nuclear plasmid of Dictyostelium discoideum is presented. Previous studies have shown nine transcripts which map to five different regions of Ddp1, suggesting alternative transcription initiation sites and/or post-transcriptional processing. The sequence presented here shows five long open reading frames corresponding to previously known transcribed regions, as well as an additional reading frame, in the region of the presumed origin of replication. Two of the predicted proteins from the Ddp1 reading frames have potential leader sequences and transmembrane domains, while the rest, if translated, would encode soluble proteins. One of these has both leucine zipper and zinc finger-like motifs. Sequences upstream of the reading frames show strong similarities to chromosomal promoter elements, suggesting that transcription of at least some of the plasmid-encoded genes is regulated by factors which regulate chromosomal transcription in this organism. The region containing the presumptive origin of replication contains the promoters of the major growth-specific gene, as well as a second gene; thus, the processes of transcription and replication of Ddp1 may be intimately linked. The origin-encompassing region has a long homopurine/homopyrimidine stretch, which is similar to sequences shown in vitro to be capable of forming a triple helix structure through Hoogsteen base pairing. Possible roles for these sequences and the products of the ORFs in plasmid maintenance are discussed."xsd:string
http://purl.uniprot.org/citations/8029325http://purl.org/dc/terms/identifier"doi:10.1006/plas.1994.1019"xsd:string
http://purl.uniprot.org/citations/8029325http://purl.org/dc/terms/identifier"doi:10.1006/plas.1994.1019"xsd:string
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/author"Hughes J.E."xsd:string
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/author"Hughes J.E."xsd:string
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/author"Farrar N.A."xsd:string
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/author"Farrar N.A."xsd:string
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/author"Williams K.L."xsd:string
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/author"Williams K.L."xsd:string
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/author"Welker D.L."xsd:string
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/author"Welker D.L."xsd:string
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/author"Kiyosawa H."xsd:string
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/author"Kiyosawa H."xsd:string
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/name"Plasmid"xsd:string
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/name"Plasmid"xsd:string
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/pages"184-195"xsd:string
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/pages"184-195"xsd:string
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/title"Nucleotide sequence of Ddp1, a high copy number nuclear plasmid of Dictyostelium discoideum."xsd:string
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/title"Nucleotide sequence of Ddp1, a high copy number nuclear plasmid of Dictyostelium discoideum."xsd:string
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/volume"31"xsd:string
http://purl.uniprot.org/citations/8029325http://purl.uniprot.org/core/volume"31"xsd:string