http://purl.uniprot.org/citations/8078588 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8078588 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8078588 | http://www.w3.org/2000/01/rdf-schema#comment | "Transforming growth factor-beta (TGF-beta) inhibits cell proliferation by inducing a G1-phase cell cycle arrest. Normal progression through G1 is promoted by the activity of the cyclin-dependent protein kinases CDK4 and CDK6 (ref. 2), which are inhibited by the protein p16INK4. We have isolated a new member of the p16INK4 family, p15INK4B. p15 expression is induced approximately 30-fold in human keratinocytes by treatment with TGF-beta, suggesting that p15 may act as an effector of TGF-beta-mediated cell cycle arrest. The gene encoding p15 is located on chromosome 9 adjacent to the p16 gene at a frequent site of chromosomal abnormality in human tumours (9p21)."xsd:string |
http://purl.uniprot.org/citations/8078588 | http://purl.org/dc/terms/identifier | "doi:10.1038/371257a0"xsd:string |
http://purl.uniprot.org/citations/8078588 | http://purl.org/dc/terms/identifier | "doi:10.1038/371257a0"xsd:string |
http://purl.uniprot.org/citations/8078588 | http://purl.uniprot.org/core/author | "Beach D."xsd:string |
http://purl.uniprot.org/citations/8078588 | http://purl.uniprot.org/core/author | "Beach D."xsd:string |
http://purl.uniprot.org/citations/8078588 | http://purl.uniprot.org/core/author | "Hannon G.J."xsd:string |
http://purl.uniprot.org/citations/8078588 | http://purl.uniprot.org/core/author | "Hannon G.J."xsd:string |
http://purl.uniprot.org/citations/8078588 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/8078588 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/8078588 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
http://purl.uniprot.org/citations/8078588 | http://purl.uniprot.org/core/name | "Nature"xsd:string |
http://purl.uniprot.org/citations/8078588 | http://purl.uniprot.org/core/pages | "257-261"xsd:string |
http://purl.uniprot.org/citations/8078588 | http://purl.uniprot.org/core/pages | "257-261"xsd:string |
http://purl.uniprot.org/citations/8078588 | http://purl.uniprot.org/core/title | "p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest."xsd:string |
http://purl.uniprot.org/citations/8078588 | http://purl.uniprot.org/core/title | "p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest."xsd:string |
http://purl.uniprot.org/citations/8078588 | http://purl.uniprot.org/core/volume | "371"xsd:string |
http://purl.uniprot.org/citations/8078588 | http://purl.uniprot.org/core/volume | "371"xsd:string |
http://purl.uniprot.org/citations/8078588 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8078588 |
http://purl.uniprot.org/citations/8078588 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8078588 |
http://purl.uniprot.org/citations/8078588 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8078588 |
http://purl.uniprot.org/citations/8078588 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8078588 |
http://purl.uniprot.org/uniprot/P42772 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/8078588 |
http://purl.uniprot.org/embl-cds/AAA50282.1 | http://purl.uniprot.org/core/citation | http://purl.uniprot.org/citations/8078588 |