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http://purl.uniprot.org/citations/8093038http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8093038http://www.w3.org/2000/01/rdf-schema#comment"The primary structure of mouse MAP kinase-activated protein (MAPKAP) kinase 2 contains a proline-rich N-terminal region which might function as a src-homology 3 (SH3) domain-binding motif in vivo. To demonstrate the ability of this region to bind SH3 domains, we analyzed the interaction of the SH3 domain of the protein tyrosine kinase c-abl with MAPKAP kinase 2. It is demonstrated, that the proline-rich region specifically binds c-abl-SH3 domain in vitro. Furthermore, it is shown, that deletion of this proline-rich region does not significantly influence the substrate binding properties of the enzyme when analyzed with the substrate small heat shock protein Hsp25. The data suggest that the proline-rich region of MAPKAP kinase 2 could interact with proteins containing SH3-domains also in vivo regulating its cellular localization and/or modulating its enzymatic properties."xsd:string
http://purl.uniprot.org/citations/8093038http://purl.org/dc/terms/identifier"doi:10.1006/bbrc.1994.2308"xsd:string
http://purl.uniprot.org/citations/8093038http://purl.uniprot.org/core/author"Engel K."xsd:string
http://purl.uniprot.org/citations/8093038http://purl.uniprot.org/core/author"Gaestel M."xsd:string
http://purl.uniprot.org/citations/8093038http://purl.uniprot.org/core/author"Plath K."xsd:string
http://purl.uniprot.org/citations/8093038http://purl.uniprot.org/core/author"Schwedersky G."xsd:string
http://purl.uniprot.org/citations/8093038http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/8093038http://purl.uniprot.org/core/name"Biochem Biophys Res Commun"xsd:string
http://purl.uniprot.org/citations/8093038http://purl.uniprot.org/core/pages"1188-1194"xsd:string
http://purl.uniprot.org/citations/8093038http://purl.uniprot.org/core/title"Characterization of the proline-rich region of mouse MAPKAP kinase 2: influence on catalytic properties and binding to the c-abl SH3 domain in vitro."xsd:string
http://purl.uniprot.org/citations/8093038http://purl.uniprot.org/core/volume"203"xsd:string
http://purl.uniprot.org/citations/8093038http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8093038
http://purl.uniprot.org/citations/8093038http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/8093038
http://purl.uniprot.org/uniprot/#_A0A087WSN7-mappedCitation-8093038http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8093038
http://purl.uniprot.org/uniprot/#_A0A1W2P7V9-mappedCitation-8093038http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8093038
http://purl.uniprot.org/uniprot/#_A0A1W2P769-mappedCitation-8093038http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8093038
http://purl.uniprot.org/uniprot/#_A0A4P3APB9-mappedCitation-8093038http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8093038
http://purl.uniprot.org/uniprot/#_D3Z446-mappedCitation-8093038http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8093038
http://purl.uniprot.org/uniprot/#_P49138-mappedCitation-8093038http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8093038
http://purl.uniprot.org/uniprot/#_Q63932-mappedCitation-8093038http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8093038
http://purl.uniprot.org/uniprot/#_Q3USU3-mappedCitation-8093038http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8093038
http://purl.uniprot.org/uniprot/#_M0QWN2-mappedCitation-8093038http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8093038
http://purl.uniprot.org/uniprot/#_Q8CB46-mappedCitation-8093038http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8093038
http://purl.uniprot.org/uniprot/#_Q3U2P8-mappedCitation-8093038http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/8093038