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http://purl.uniprot.org/citations/8095488http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8095488http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8095488http://www.w3.org/2000/01/rdf-schema#comment"Nucleotide sequence analysis of the ERBB2 proton-oncogene in human breast tumors revealed a sequence variation at codons 654 and 655, corresponding to the transmembrane region of the protein. To investigate this polymorphism, genotyping of 340 unrelated individuals was conducted by allele-specific oligonucleotide (ASO) hybridization of DNA amplified from the ERBB2 transmembrane region. ASO hybridization under competition conditions allowed rapid and unambiguous assignment of alleles and revealed the occurrence of a new allele, B3, encoding Val-Val. The sensitivity and the specificity of the ASO competition hybridization technique indicate that the method is generally applicable to the analysis of polymorphisms in the human genome."xsd:string
http://purl.uniprot.org/citations/8095488http://purl.org/dc/terms/identifier"doi:10.1006/geno.1993.1081"xsd:string
http://purl.uniprot.org/citations/8095488http://purl.org/dc/terms/identifier"doi:10.1006/geno.1993.1081"xsd:string
http://purl.uniprot.org/citations/8095488http://purl.uniprot.org/core/author"Wallace R.B."xsd:string
http://purl.uniprot.org/citations/8095488http://purl.uniprot.org/core/author"Wallace R.B."xsd:string
http://purl.uniprot.org/citations/8095488http://purl.uniprot.org/core/author"Low J."xsd:string
http://purl.uniprot.org/citations/8095488http://purl.uniprot.org/core/author"Low J."xsd:string
http://purl.uniprot.org/citations/8095488http://purl.uniprot.org/core/author"Wu A.M."xsd:string
http://purl.uniprot.org/citations/8095488http://purl.uniprot.org/core/author"Wu A.M."xsd:string
http://purl.uniprot.org/citations/8095488http://purl.uniprot.org/core/author"Ehsani A."xsd:string
http://purl.uniprot.org/citations/8095488http://purl.uniprot.org/core/author"Ehsani A."xsd:string
http://purl.uniprot.org/citations/8095488http://purl.uniprot.org/core/date"1993"xsd:gYear
http://purl.uniprot.org/citations/8095488http://purl.uniprot.org/core/date"1993"xsd:gYear
http://purl.uniprot.org/citations/8095488http://purl.uniprot.org/core/name"Genomics"xsd:string
http://purl.uniprot.org/citations/8095488http://purl.uniprot.org/core/name"Genomics"xsd:string
http://purl.uniprot.org/citations/8095488http://purl.uniprot.org/core/pages"426-429"xsd:string
http://purl.uniprot.org/citations/8095488http://purl.uniprot.org/core/pages"426-429"xsd:string
http://purl.uniprot.org/citations/8095488http://purl.uniprot.org/core/title"Characterization of a new allele of the human ERBB2 gene by allele-specific competition hybridization."xsd:string
http://purl.uniprot.org/citations/8095488http://purl.uniprot.org/core/title"Characterization of a new allele of the human ERBB2 gene by allele-specific competition hybridization."xsd:string
http://purl.uniprot.org/citations/8095488http://purl.uniprot.org/core/volume"15"xsd:string
http://purl.uniprot.org/citations/8095488http://purl.uniprot.org/core/volume"15"xsd:string
http://purl.uniprot.org/citations/8095488http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8095488
http://purl.uniprot.org/citations/8095488http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8095488