| http://purl.uniprot.org/citations/8111975 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8111975 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8111975 | http://www.w3.org/2000/01/rdf-schema#comment | "The Caenorhabditis elegans XX animal possesses a hermaphrodite germ line, producing first sperm, then oocytes. In this paper, we report the genetic identification of five genes, mog-2, mog-3, mog-4, mog-5, and mog-6, that influence the hermaphrodite switch from spermatogenesis to oogenesis. In mog-2-mog-6 mutants, spermatogenesis continues past the time at which hermaphrodites normally switch into oogenesis and no oocytes are observed. Therefore, in these mutants, germ cells are transformed from a female fate (oocyte) to a male fate (sperm). The fem-3 gene is one of five genes that acts at the end of the germline sex determination pathway to direct spermatogenesis. Analyses of mog;fem-3 double mutants suggest that the mog-2-mog-6 genes act before fem-3; thus these genes may be in a position to negatively regulate fem-3 or one of the other terminal regulators of germline sex determination. Double mutants of fem-3 and any one of the mog mutations make oocytes. Using these double mutants, we show that oocytes from any mog;fem-3 double mutant are defective in their ability to support embryogenesis. This maternal effect lethality indicates that each of the mog genes is required for embryogenesis. The two defects in mog-2-mog-6 mutants are similar to those of mog-1: all six mog genes eliminate the sperm/oocyte switch in hermaphrodites and cause maternal effect lethality. We propose that the mog-2-mog-6 mutations identify genes that act with mog-1 to effect the sperm/oocyte switch. We further speculate that the mog-1-mog-6 mutations all interfere with translational controls of fem-3 and other maternal mRNAs."xsd:string |
| http://purl.uniprot.org/citations/8111975 | http://purl.org/dc/terms/identifier | "doi:10.1002/dvg.1020140608"xsd:string |
| http://purl.uniprot.org/citations/8111975 | http://purl.org/dc/terms/identifier | "doi:10.1002/dvg.1020140608"xsd:string |
| http://purl.uniprot.org/citations/8111975 | http://purl.uniprot.org/core/author | "Schedl T."xsd:string |
| http://purl.uniprot.org/citations/8111975 | http://purl.uniprot.org/core/author | "Schedl T."xsd:string |
| http://purl.uniprot.org/citations/8111975 | http://purl.uniprot.org/core/author | "Kimble J."xsd:string |
| http://purl.uniprot.org/citations/8111975 | http://purl.uniprot.org/core/author | "Kimble J."xsd:string |
| http://purl.uniprot.org/citations/8111975 | http://purl.uniprot.org/core/author | "Graham P.L."xsd:string |
| http://purl.uniprot.org/citations/8111975 | http://purl.uniprot.org/core/author | "Graham P.L."xsd:string |
| http://purl.uniprot.org/citations/8111975 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8111975 | http://purl.uniprot.org/core/date | "1993"xsd:gYear |
| http://purl.uniprot.org/citations/8111975 | http://purl.uniprot.org/core/name | "Dev. Genet."xsd:string |
| http://purl.uniprot.org/citations/8111975 | http://purl.uniprot.org/core/name | "Dev. Genet."xsd:string |
| http://purl.uniprot.org/citations/8111975 | http://purl.uniprot.org/core/pages | "471-484"xsd:string |
| http://purl.uniprot.org/citations/8111975 | http://purl.uniprot.org/core/pages | "471-484"xsd:string |
| http://purl.uniprot.org/citations/8111975 | http://purl.uniprot.org/core/title | "More mog genes that influence the switch from spermatogenesis to oogenesis in the hermaphrodite germ line of Caenorhabditis elegans."xsd:string |
| http://purl.uniprot.org/citations/8111975 | http://purl.uniprot.org/core/title | "More mog genes that influence the switch from spermatogenesis to oogenesis in the hermaphrodite germ line of Caenorhabditis elegans."xsd:string |
| http://purl.uniprot.org/citations/8111975 | http://purl.uniprot.org/core/volume | "14"xsd:string |
| http://purl.uniprot.org/citations/8111975 | http://purl.uniprot.org/core/volume | "14"xsd:string |
| http://purl.uniprot.org/citations/8111975 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8111975 |
| http://purl.uniprot.org/citations/8111975 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8111975 |
| http://purl.uniprot.org/citations/8111975 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8111975 |
| http://purl.uniprot.org/citations/8111975 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8111975 |