http://purl.uniprot.org/citations/8150085 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8150085 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8150085 | http://www.w3.org/2000/01/rdf-schema#comment | "We purified three homologous antimicrobial peptides ('gallinacins') from chicken leukocytes, examined their antimicrobial activity in vitro, and established their primary sequences by a combination of gas phase microsequencing and on-line LC-ESI-MS analysis of endo- and exoprotease peptide digests. The peptides contained 36-39 amino acid residues, were relatively cationic due to their numerous lysine and arginine residues, and each contained 3 intramolecular cystine disulfide bonds. Gallinacins showed primary sequence homology to the recently delineated beta-defensin family, heretofore found only in the respiratory epithelial cells and neutrophils of cattle, suggesting that beta-defensins originated at least 250 million years ago, before avian and mammalian lineages diverged. The 9 invariant residues (6 cysteines, 2 glycines and 1 proline) common to avian gallinacins and bovine beta-defensins are likely to constitute the essential primary structural motif of this ancient family of host-defense peptides."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.org/dc/terms/identifier | "doi:10.1016/0014-5793(94)80517-2"xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.org/dc/terms/identifier | "doi:10.1016/0014-5793(94)80517-2"xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/author | "Tan L."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/author | "Tan L."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/author | "Swiderek K.M."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/author | "Swiderek K.M."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/author | "Lee T.D."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/author | "Lee T.D."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/author | "Lehrer R.I."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/author | "Lehrer R.I."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/author | "Aleshina G.M."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/author | "Aleshina G.M."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/author | "Kokryakov V.N."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/author | "Kokryakov V.N."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/author | "Harwig S.S.L."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/author | "Harwig S.S.L."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/author | "Shamova O.V."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/author | "Shamova O.V."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/author | "Panyutich E.A."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/author | "Panyutich E.A."xsd:string |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/8150085 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |