http://purl.uniprot.org/citations/8163491 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8163491 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/8163491 | http://www.w3.org/2000/01/rdf-schema#comment | "The nmt1+ gene of the fission yeast Schizosaccharomyces pombe is subject to transcriptional repression mediated by thiamine. The promoter of nmt1+ has been used to construct a series of vectors that are now commonly used for the regulated expression of genes in S. pombe. In this report, we described ntf1+, a gene involved in regulating nmt1+ expression. The ntf1+ gene was cloned in a high copy suppressor screen that utilized a construct, nmt1:wee1+, in which expression of the mitotic inhibitor Wee1 tyrosine kinase was placed under the control of the nmt1 promoter. ntf1+ encodes a 706-amino acid protein that shares substantial homology with a family of Cys6 zinc finger-containing transcription factors typified by GAL4 from Saccharomyces cerevisiae. Increased gene dosage of ntf1+ greatly increases both the repressed and derepressed activity of the nmt1 promoter. Cells having a disrupted version of ntf1+ are viable thiamine prototrophs, but basal expression from the nmt1 promoter is greatly reduced. These data demonstrate that Ntf1 plays an important role in regulating nmt1 expression."xsd:string |
http://purl.uniprot.org/citations/8163491 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(17)32660-1"xsd:string |
http://purl.uniprot.org/citations/8163491 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0021-9258(17)32660-1"xsd:string |
http://purl.uniprot.org/citations/8163491 | http://purl.uniprot.org/core/author | "Russell P."xsd:string |
http://purl.uniprot.org/citations/8163491 | http://purl.uniprot.org/core/author | "Russell P."xsd:string |
http://purl.uniprot.org/citations/8163491 | http://purl.uniprot.org/core/author | "Bueno A."xsd:string |
http://purl.uniprot.org/citations/8163491 | http://purl.uniprot.org/core/author | "Bueno A."xsd:string |
http://purl.uniprot.org/citations/8163491 | http://purl.uniprot.org/core/author | "Tang C.S.L."xsd:string |
http://purl.uniprot.org/citations/8163491 | http://purl.uniprot.org/core/author | "Tang C.S.L."xsd:string |
http://purl.uniprot.org/citations/8163491 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/8163491 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
http://purl.uniprot.org/citations/8163491 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/8163491 | http://purl.uniprot.org/core/name | "J. Biol. Chem."xsd:string |
http://purl.uniprot.org/citations/8163491 | http://purl.uniprot.org/core/pages | "11921-11926"xsd:string |
http://purl.uniprot.org/citations/8163491 | http://purl.uniprot.org/core/pages | "11921-11926"xsd:string |
http://purl.uniprot.org/citations/8163491 | http://purl.uniprot.org/core/title | "ntf1+ encodes a 6-cysteine zinc finger-containing transcription factor that regulates the nmt1 promoter in fission yeast."xsd:string |
http://purl.uniprot.org/citations/8163491 | http://purl.uniprot.org/core/title | "ntf1+ encodes a 6-cysteine zinc finger-containing transcription factor that regulates the nmt1 promoter in fission yeast."xsd:string |
http://purl.uniprot.org/citations/8163491 | http://purl.uniprot.org/core/volume | "269"xsd:string |
http://purl.uniprot.org/citations/8163491 | http://purl.uniprot.org/core/volume | "269"xsd:string |
http://purl.uniprot.org/citations/8163491 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8163491 |
http://purl.uniprot.org/citations/8163491 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/8163491 |
http://purl.uniprot.org/citations/8163491 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8163491 |
http://purl.uniprot.org/citations/8163491 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/8163491 |