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http://purl.uniprot.org/citations/8163491http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8163491http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/8163491http://www.w3.org/2000/01/rdf-schema#comment"The nmt1+ gene of the fission yeast Schizosaccharomyces pombe is subject to transcriptional repression mediated by thiamine. The promoter of nmt1+ has been used to construct a series of vectors that are now commonly used for the regulated expression of genes in S. pombe. In this report, we described ntf1+, a gene involved in regulating nmt1+ expression. The ntf1+ gene was cloned in a high copy suppressor screen that utilized a construct, nmt1:wee1+, in which expression of the mitotic inhibitor Wee1 tyrosine kinase was placed under the control of the nmt1 promoter. ntf1+ encodes a 706-amino acid protein that shares substantial homology with a family of Cys6 zinc finger-containing transcription factors typified by GAL4 from Saccharomyces cerevisiae. Increased gene dosage of ntf1+ greatly increases both the repressed and derepressed activity of the nmt1 promoter. Cells having a disrupted version of ntf1+ are viable thiamine prototrophs, but basal expression from the nmt1 promoter is greatly reduced. These data demonstrate that Ntf1 plays an important role in regulating nmt1 expression."xsd:string
http://purl.uniprot.org/citations/8163491http://purl.org/dc/terms/identifier"doi:10.1016/s0021-9258(17)32660-1"xsd:string
http://purl.uniprot.org/citations/8163491http://purl.org/dc/terms/identifier"doi:10.1016/s0021-9258(17)32660-1"xsd:string
http://purl.uniprot.org/citations/8163491http://purl.uniprot.org/core/author"Russell P."xsd:string
http://purl.uniprot.org/citations/8163491http://purl.uniprot.org/core/author"Russell P."xsd:string
http://purl.uniprot.org/citations/8163491http://purl.uniprot.org/core/author"Bueno A."xsd:string
http://purl.uniprot.org/citations/8163491http://purl.uniprot.org/core/author"Bueno A."xsd:string
http://purl.uniprot.org/citations/8163491http://purl.uniprot.org/core/author"Tang C.S.L."xsd:string
http://purl.uniprot.org/citations/8163491http://purl.uniprot.org/core/author"Tang C.S.L."xsd:string
http://purl.uniprot.org/citations/8163491http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/8163491http://purl.uniprot.org/core/date"1994"xsd:gYear
http://purl.uniprot.org/citations/8163491http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/8163491http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/8163491http://purl.uniprot.org/core/pages"11921-11926"xsd:string
http://purl.uniprot.org/citations/8163491http://purl.uniprot.org/core/pages"11921-11926"xsd:string
http://purl.uniprot.org/citations/8163491http://purl.uniprot.org/core/title"ntf1+ encodes a 6-cysteine zinc finger-containing transcription factor that regulates the nmt1 promoter in fission yeast."xsd:string
http://purl.uniprot.org/citations/8163491http://purl.uniprot.org/core/title"ntf1+ encodes a 6-cysteine zinc finger-containing transcription factor that regulates the nmt1 promoter in fission yeast."xsd:string
http://purl.uniprot.org/citations/8163491http://purl.uniprot.org/core/volume"269"xsd:string
http://purl.uniprot.org/citations/8163491http://purl.uniprot.org/core/volume"269"xsd:string
http://purl.uniprot.org/citations/8163491http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8163491
http://purl.uniprot.org/citations/8163491http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/8163491
http://purl.uniprot.org/citations/8163491http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/8163491
http://purl.uniprot.org/citations/8163491http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/8163491