| http://purl.uniprot.org/citations/8170356 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/8170356 | http://www.w3.org/2000/01/rdf-schema#comment | "Melatonin is synthesized from serotonin by the enzymes serotonin N-acetyltransferase (SNAT) and hydroxyindole-O-methyl-transferase (HIOMT). We have previously reported that C57BL/6 mice do not have SNAT activity because of a mutation in an autosomal gene which is responsible for the absence of normal SNAT activity. In the present study, we have tried to map the loci of Nat-2 (the locus controlling SNAT activity) on chromosomes using a set of the BxH recombinant inbred strains which were derived from an initial cross between C3H/He with SNAT and C57BL/6 without the enzyme. Based on strain distribution patterns (SDPs), a close linkage on chromosome 11 was found between Nat-2, Es-3 (esterase-3), Glk (the locus controlling galactokinase activity) and Myla (myosin alkali light chains expressed in cardiac atrial muscle). The linkage between Nat-2 and Es-3 was confirmed by a conventional linkage test and the recombination frequency between these loci was estimated to be 16.1 +/-3.6% (mean +/- S.E.M.)."xsd:string |
| http://purl.uniprot.org/citations/8170356 | http://purl.org/dc/terms/identifier | "doi:10.1016/0169-328x(94)90266-6"xsd:string |
| http://purl.uniprot.org/citations/8170356 | http://purl.uniprot.org/core/author | "Hasegawa M."xsd:string |
| http://purl.uniprot.org/citations/8170356 | http://purl.uniprot.org/core/author | "Goto M."xsd:string |
| http://purl.uniprot.org/citations/8170356 | http://purl.uniprot.org/core/author | "Ebihara S."xsd:string |
| http://purl.uniprot.org/citations/8170356 | http://purl.uniprot.org/core/author | "Oshima I."xsd:string |
| http://purl.uniprot.org/citations/8170356 | http://purl.uniprot.org/core/date | "1994"xsd:gYear |
| http://purl.uniprot.org/citations/8170356 | http://purl.uniprot.org/core/name | "Brain Res Mol Brain Res"xsd:string |
| http://purl.uniprot.org/citations/8170356 | http://purl.uniprot.org/core/pages | "349-354"xsd:string |
| http://purl.uniprot.org/citations/8170356 | http://purl.uniprot.org/core/title | "The locus controlling pineal serotonin N-acetyltransferase activity (Nat-2) is located on mouse chromosome 11."xsd:string |
| http://purl.uniprot.org/citations/8170356 | http://purl.uniprot.org/core/volume | "21"xsd:string |
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